ANTI-NOCICEPTION

作品数：7被引量：9H指数：2
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相关领域：医药卫生更多>>
相关期刊：《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》《Progress in Natural Science:Materials International》《Traditional Medicine Research》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
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Inhibition of Nav1.7 channel by a novel blocker QLS-81 for alleviation of neuropathic pain被引量：2
《Acta Pharmacologica Sinica》2021年第8期1235-1247,共13页He-ling Niu Ya-ni Liu Deng-qi Xue Li-ying Dong Hui-jie Liu Jing Wang Yi-lin Zheng An-ruo Zou Li-ming Shao KeWei Wang 
supported by research grants from the Science and Technology Program of Guangdong(2018B030334001);the Ministry of Science and Technology of China(2018ZX09711001-004-006)awarded to KWW;the National Natural Science Foundation of Shandong Province(ZR2020QH100).
Voltage-gated sodium channel Nav1.7 robustly expressed in peripheral nociceptive neurons has been considered as a therapeutic target for chronic pain,but there is no selective Nav1.7 inhibitor available for therapy of...
关键词：Nav1.7 ralfinamide QLS-81 neuropathic pain inflammatory pain ANTI-NOCICEPTION 
The coastal medicinal plant Vitex rotundifolia: a mini-review on its bioactive compounds and pharmacological activity
《Traditional Medicine Research》2021年第2期1-10,共10页Nurul Husna Azizul Wan Amir Nizam Wan Ahmad Nurul Laili Rosli Muhammad Aniq Hamzah Mohd Azmi Choo En Liang Noor Wini Mazlan Suvik Assaw 
Author would like to thank School of Health Sciences,Universiti Sains Malaysia and Universiti Malaysia Terengganu for providing the facilities to support this project;This project is fully supported by Fundamental Research Grant Scheme Vot No.59479 from Ministry of Higher Education Malaysia.
Humans have long used natural remedies like plants and herbs to treat disease.Furthermore,research has been ongoing to find alternative pharmaceutical drugs based on traditionally used plants,as natural products show ...
关键词：Vitex rotundifolia Fructus viticis Marine plants ANTI-INFLAMMATION ANTI-NOCICEPTION ANTIOXIDANT 
The aconitine analog bulleyaconitine A exhibits anti-hypersensitivity through direct stimulation of dynorphin A release from spinal microglia in the rat model of neuropathy
《中国药理学通报》2015年第B11期74-74,共1页
Aim Aconitine and its structurally-related diterpenoid alkaloids have been shown to interact differential- ly with neuronal voltage-dependent sodium channels and be responsible for their analgesia and toxicity. Bulley...
关键词：bulleyaconitine A (BAA or BLA) ACONITINE ANTI-NOCICEPTION pain HYPERSENSITIVITY morphine toler-ance to ANTI-NOCICEPTION SPINAL cord MICROGLIA DYNORPHIN A. 
Prophylactic effects of asiaticoside-based standardized extract of Centella asiatica(L.) Urban leaves on experimental migraine: Involvement of 5HT1A/1B receptors被引量：1
《Chinese Journal of Natural Medicines》2015年第4期274-282,共9页Vijeta Bobade Subhash L.Bodhankar Urmila Aswar Vishwaraman Mohan Prasad Thakurdesai 
supported by Indus Biotech Private Limited,Pune
The present study aimed at evaluation of prophylactic efficacy and possible mechanisms of asiaticoside （AS） based standardized extract of Centella asiatica （L.） Urban leaves （INDCA） in animal models of migraine....
关键词：Centella asiatica （L.） Urban Experimental migraine ANTI-NOCICEPTION Serotonin  5HTI A and 5HT1B receptors 
Addition of Capsaicin to Local Anesthetics for Spinal Anesthesia in Rats Shortens Motor Deficits and Prolongs Anti-Nociception
《Open Journal of Anesthesiology》2014年第6期123-130,共8页Charles H. Wang Jeffrey C. Wang Mieke A. Soens Peter Gerner Gary Strichartz 
Background and Objectives: Sensory-selective anesthesia, greater or longer-lasting anti-nociception than motor or autonomic deficits, is often clinically desirable but traditional local anesthetics rarely have such se...
关键词：Spinal ANESTHESIA Differential BLOCKADE ANALGESIA TRPV-1 
Suppression of complete Freund＇s adjuvant-induced adjuvant arthritis by cobratoxin被引量：6
《Acta Pharmacologica Sinica》2009年第2期219-227,共9页Yan-li LIU Hai-ming LIN Rong ZOU Jun-chao WU Rong HAN Laurence N RAYMOND Paul F REID Zheng-hong QIN 
Aim： Cobratoxin （CTX）, the long-chain α-neurotoxin from Thailand cobra venom, has been demonstrated to have analgesic action in rodent pain models. The present study evaluated the anti-inflammatory and anti-nocice...
关键词：cobratoxin adjuvant arthritis ANTI-INFLAMMATORY ANTI-NOCICEPTION α7-nicotinic acetylcholine receptor 
Anti-nociceptive role of neuropeptide Y in the nucleus accumbens in rats with inflammation, an effect modulated by mu- and kappa-opioid receptors
《Progress in Natural Science:Materials International》2006年第2期133-141,共9页LI Jinju YU Longchuan 
National Natural Science Foundation of China (Grant No. 30370455)
Recent study in our laboratory showed that neuropeptide Y （NPY） plays an antinociceptive role in the nucleus accum hens （NAc） in intact rats. The present study was performed to further investigate the effect of NP...
关键词：nucleus accumbens  neuropeptide Y  Y1 receptor  carrageenan anti-nociception  μ- and κ-opioid receptors 
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