云南高校图书馆联盟文献共享服务平台- BLOCKADE

BLOCKADE: 作品数：255被引量：795H指数：15; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：司伟李子福杨祥良李峥陈云飞更多>>; 相关机构：华中科技大学同济大学东北师范大学东南大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金湖北省自然科学基金更多>>

Oncolytic adenovirus H101 enhances the anti-tumor effects of PD-1 blockade via CD47 downregulation in tumor cells: 《Oncology Research》2025年第5期1161-1172,共12页CHENXIAO QIAO YIPENG XU YEDIE HE ZHIJIAN CAI HUA WANG; supported by Techpool Bio-Pharma Co.,Ltd.(grant no.AKR-S005).; Objective:To investigate the anti-tumor effects of an E1B55KD-deleted oncolytic adenovirus,H101,in combination with a humanized anti-PD-1(Programmed cell death protein 1)monoclonal antibody,Camrelizumab.Methods:Anti-t...; 关键词：Cancer Oncolytic adenovirus Macrophage CD47 Programmed cell death protein 1 blockade(PD-1 blockade)

Irreversible electroporation combined with anti-programmed cell death protein 1 therapy promotes tumor antigen-specific CD8+T cell response: 《World Journal of Gastrointestinal Oncology》2025年第3期237-245,共9页Yang-Yang Ma Xiao-Hua Wang Jian-Ying Zeng Ji-Bing Chen Li-Zhi Niu; Science and Technology Program of Guangzhou,No.202102010077;International Science Foundation of Guangzhou Fuda Cancer Hospital,No.Y2020-ZD-03.; BACKGROUND Irreversible electroporation(IRE)is a novel local tumor ablation approach with the potential to activate the host’s immune system.However,this approach is insufficient to prevent cancer progression,and com...; 关键词：Irreversible electroporation Pancreatic cancer Programmed cell death protein 1 blockade CD8+T cell Anticancer immunity

An epH-driven DNA nanodevice for impeding metastasis in vivo by selectively blocking cell signaling: 《National Science Review》2025年第3期255-266,共12页Kun Yuan Hong-Min Meng Hongzhi Sun Lingbo Qu Zhaohui Li Weihong Tan; supported by the Natural Science Foundation of Henan(232300421021 and 242300421121);the National Natural Science Foundation of China(22374136,22274143);Henan Fundamental Research Leading Talent,and the National Key Research and Development Program(2023YFF0714402 and 2023YFF0714400).; Invasion and metastasis dominate tumor progression,causing a substantial proportion of cancer-related deaths.However,the efficacy of current antimetastatic treatments is hampered by the dearth of targeted therapeutics...; 关键词：antimetastatic therapy cellular signaling blockade DNA nanodevice extracellular pH tailored bioregulation

NG2 Glia:The Guardians Against Prion‑induced Neurotoxicity Through Prostaglandin E2 Blockade: 《Neuroscience Bulletin》2025年第3期539-542,共4页Shu Feng Emily Parker Timon Cheng‑Yi Liu Luodan Yang; supported by the National Natural Science Foundation of China(32300959);a Guangzhou Scientific Research Grant(SL2024A04J00578);the SCNU Young Faculty Development Program(22KJ04).; Neuron glia antigen-2(NG2)glia,also known as oligodendrocyte precursor cells(OPCs),are essential for maintaining the normal function and structure of the central nervous system(CNS)due to their supportive role[1].Unde...; 关键词：maintaining normal function structure myelin sheath axons oligodendrocyte precursor cells opcs receiving synaptic input neurons NEUROTOXICITY PRION central nervous system cns due ng glia

Encrypting Cancer’s Morse Code: The Synergistic Power of CD47-SIRPα Blockade and Tyrosine Kinase Inhibition: 《International Journal of Clinical Medicine》2025年第2期135-153,共19页Mahamud Hirsi Yahya Lahrach Abdirahman Mohamud Abdirahman Amina Nazir Mohamed Abshir Barre Yasmine Yusuf Hussein Dinle Abdulrahman Wajih Alkhatib Biradar Rohan Nagendrappa; Modern medicine faces the formidable challenge of cancer because of its ability to evade immune surveillance and cultivate resistance to conventional therapies. Cancer cells, when overexpressed with CD47, send a “don...; 关键词：CD47 Tyrosine Kinase Inhibitors Cancer Immune Evasion Tumor Microenvironment Targeted Cancer Therapy Immune Checkpoint Inhibitors

Photon blockade in a double-transmon system with ultrastrong coupling: 《Communications in Theoretical Physics》2025年第2期81-86,共6页Tian Tian Xianhe Zhu Xi Tian; supported by the National Science Foundation of China(Grant No.12105026);Climbing Plan of Changchun University(Grant No.ZKP202010);Educational Commission of Jilin Province of China(Grant No.JJKH20230663KJ)。; The circuit quantum electrodynamics(QED)system has brought us into an ultrastrong and deep coupling regime in the light-matter interaction community,in which the quantum effect has attracted significant interest.In th...; 关键词：ultrastrong coupling master equation photon blockade

Circulating immunological transcriptomic profile identifies DDX3Y and USP9Y on the Y chromosome as promising biomarkers for predicting response to programmed death 1/programmed death ligand 1 blockade: 《Chinese Medical Journal》2025年第3期364-366,共3页Liting You Zhaodan Xin Feifei Na Min Chen Yang Wen Jin Li Jiajia Song Ling Bai Jianzhao Zhai Xiaohan Zhou Binwu Ying Juan Zhou; National Natural Science Foundation of China(No.NSFC82372331);Project of Science and Technology Department of Sichuan Province(Nos.2024NSFSC1551 and 2023NSFSC0716); To the Editor:Immune checkpoint inhibitors(ICIs)have shown remarkable clinical responses;however,their efficacy remains limited to a small subset of patients.Peripheral blood mononuclear cells(PBMCs)offer an effective...; 关键词：circulating immunological transcriptomic profile blood mononuclear cells pbmcs offer programmed death assess tumor immune status programmed death ligand immune checkpoint inhibitors biomedical ethics committee ddx y

INHBA promotes tumor growth and induces resistance to PD-L1 blockade by suppressing IFN-γsignaling: 《Acta Pharmacologica Sinica》2025年第2期448-461,共14页Fang-lin Li Long-hua Gu Yong-liang Tong Run-qiu Chen Shi-yi Chen Xiao-lu Yu Nan Liu Jiang-ling Lu Yuan Si Jian-hua Sun Jing Chen Yi-ru Long Li-kun Gong; supported by Shanghai Science and Technology Committee(22S11902100);Zhongshan Municipal Bureau of Science and Technology(2020SYF08);the Department of Science and Technology of Guangdong Province(2019B090904008 and 2021B0909050003);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA 12050305).; Inhibin beta A(INHBA)and its homodimer activin A have pleiotropic effects on modulation of immune responses and tumor progression,but it remains uncertain whether tumors may release activin A to regulate anti-tumor im...; 关键词：cancer immunotherapy INHBA Activin A IFN-γsignaling pathway PD-L1

Interleukin-6 in epilepsy and its neuropsychiatric comorbidities: How to bridge the gap: 《World Journal of Psychiatry》2025年第1期1-6,共6页Xiao-Man Chen Shuo Zhang Shi-Qi Gao Michael Xu; There is growing evidence that interleukin(IL)-6 plays an important role in neurological and psychiatric disorders.This editorial comments on the study published in the recent issue of the World Journal of Psychiatry,...; 关键词：EPILEPSY INTERLEUKIN-6 Neuropsychiatric comorbidities Depression Tocilizu-mab NEUROINFLAMMATION Interleukin-6 receptor blockade

In-phase collective unconventional photon blockade and its stability in an asymmetrical cavity containing N bosonic atoms: 《Chinese Physics B》2025年第1期331-336,共6页Ying Luo Xinqin Zhang Yi Xiao Jingping Xu Haozhen Li Yaping Yang Xiuwen Xia; Project supported by the National Natural Science Foundation of China(Grant Nos.12164022 and 12174288);Natural Science Foundation of Jiangxi Province of China(Grant No.20232BAB201044);Scientific Research Foundation of the Education Department of Jiangxi Province of China(Grant No.GJJ211039);China Postdoctoral Science Foundation(Grant No.2023M732028)。; We present work on a cavity-driven QED system combining an asymmetrical Fabry–Perot cavity and N two-level atoms(TLAs)and show the convenience of simplifying from distinguishable atoms to undistinguishable bosons whe...; 关键词：unconventional photon blockade quantum nonreciprocity asymmetrical cavity

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

BLOCKADE

检索结果分析

下载全文

高级检索检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

BLOCKADE

检索结果分析

下载全文

用户登录

高级检索检索式检索