Spontaneous regression of gastric gastrinoma after resection of metastases to the lesser omentum:A case report and review of literature  

作　　者：Takeshi Okamoto Takaaki Yoshimoto Nobuyuki Ohike Aoi Fujikawa Takayoshi Kanie Katsuyuki Fukuda 

机构地区：[1]Department of Gastroenterology,St.Luke's International Hospital,Tokyo 104-8560,Japan [2]Department of Pathology,Shizuoka Cancer Center,Shizuoka 411-8777,Japan [3]Department of Surgery,St.Luke’s International Hospital,Tokyo 104-8560,Japan [4]Department of Cardiology,St.Luke’s International Hospital,Tokyo 104-8560,Japan

出　　处：《World Journal of Gastroenterology》2021年第1期129-142,共14页世界胃肠病学杂志（英文版）

摘　　要：BACKGROUND Gastric gastrinoma and spontaneous tumor regression are both very rarely encountered.We report the first case of spontaneous regression of gastric gastrinoma.CASE SUMMARY A 37-year-old man with a 9-year history of chronic abdominal pain was referred for evaluation of an 8 cm mass in the lesser omentum discovered incidentally on abdominal computed tomography.The tumor was diagnosed as grade 2 neuroendocrine neoplasm(NEN)on endoscopic ultrasound-guided fine-needle aspiration.Screening esophagogastroduodenoscopy revealed a 7 mm red polypoid lesion with central depression in the gastric antrum,also confirmed to be a grade 2 NEN.Laparoscopic removal of the abdominal mass confirmed it to be a metastatic gastrinoma lesion.The gastric lesion was subsequently diagnosed as primary gastric gastrinoma.Three months later,the gastric lesion had disappeared without treatment.The patient remains symptom-free with normal fasting serum gastrin and no recurrence of gastrinoma during 36 mo of follow-up.CONCLUSION Gastric gastrinoma may arise as a polypoid lesion in the gastric antrum.Spontaneous regression can rarely occur after biopsy.

关 键 词：Neuroendocrine neoplasm Functional tumor BIOPSY GASTRIN STOMACH Case report 

分 类 号：R735.2[医药卫生—肿瘤]