BACKGROUND Endoscopic ultrasound-guided fine-needle aspiration/biopsy(EUS-FNA/B)is the most common modality for tissue acquisition from pancreatic masses.Despite high specificity,sensitivity remains less than 90%.Auxi...
Supported by Jiangsu Science and Technology Project,No.BK20211039;the Top Talent Support Program for Young and Middle-Aged People of the Wuxi Health Committee,No.BJ2023008;the Major Program of Wuxi Medical Center,Nanjing Medical University,No.WMCM202305;the Cohort and Clinical Research Program of Wuxi Medical Center,Nanjing Medical University,No.WMCC202302;the Scientific Research Program of Wuxi Health Commission,No.Z202208;Wuxi Municipal Health and Health Commission Precision Medicine Project,No.J202104.
BACKGROUND Detecting gastric precancerous lesions(GPLs)is critical for the early diagnosis and treatment of gastric cancer.Endoscopy combined with tissue examination is an important method for detecting GPLs.However,n...
Gastrointestinal(GI)cancers,which predominantly manifest in the stomach,colorectum,liver,esophagus,and pancreas,accounting for approximately 35%of global cancer-related mortality.The advent of liquid biopsy has introd...
This editorial comments on the review by Da Silva et al,published in the World Journal of Clinical Oncology which focuses on the molecular perspectives of lung cancer.With the rapid development of molecular technology...
Cholangiocarcinoma(CCA)is a highly aggressive and heterogeneous malignancy arising from the epithelial cells of the biliary tract.The limitations of the current methods in the diagnosis of CCA highlight the urgent nee...
supported by the National Cancer Institute(grants R01CA230339 and R37CA255948).
Extracellular vesicles(EVs)are lipid bilayer-enclosed vesicles released by cells.EVs encapsulate proteins and nucleic acids of their parental cell and efficiently deliver the cargo to recipient cells.These vesicles ac...
supported by the National Natural Science Foundation of China(52375562,51875103,and 81727801);the Natural Science Foundation of Jiangsu Province(BK20190064);the“333”Project of Jiangsu Province.
Rapid diagnosis and real-time monitoring are of great important in the fight against cancer.However,most available diagnostic technologies are time-consuming and labor-intensive and are commonly invasive.Here,we descr...
supported by the National Natural Science Foundation of China(12074069);the Science Fund Program for Excellent Young Scientists of Fujian(2024J09030);the Joint Funds for the innovation of science and Technology,Fujian Province(2021Y9228);the Guiding Projects of Fujian Province(2023Y0053);the National Health and Medical Research Council(APP1173669);Cancer Australia(2010799);the Australian Research Council(FL220100059).
The epithelial-mesenchymal transition(EMT)is a critical process for cancer to metastasize by promoting invasiveness and dissemination of cancer cells in the body.Understanding and tracking EMT could improve cancer the...
Supported by The National Key R and D Program of China,No.2021YFC2500904,No.2021YFC2500905 and No.2021YFC2500900;Shandong Provincial Natural Science Foundation,No.ZR2023MH130 and No.ZR2017BH035;China Postdoctoral Science Foundation,No.2020M672073;National Natural Science Foundation of China,No.81802397.
In recent years,significant progress has been made in the application of DNA methylation for the early detection of esophageal cancer(EC).As an epigenetic modification,DNA methylation allows for noninvasive screening ...
financially supported by Major science and technology project of Yunnan Province(202302AE090022);Key Research and Development Program of Yunnan(202203AC100010);the National Natural Science Foundation of China(32160597,32160236,32371463);National Key Research and Development Program of China(2022YFC2601604);Cardiovascular Ultrasound Innovation Team of Yunnan Province(202305AS350021);Spring City Plan:the High-level Talent Promotion and Training Project of Kunming(2022SCP001);the Association Foundation Program of Yunnan Provincial Science and TechnologyDepar tment;Kunming Medical University(202101AY070001-278);the second phase of“Double-First Class”program construction of Yunnan University。
Circulating tumor cells(CTCs)are important markers for cancer.The part of tumor cells that are detached from the primary tumor or metastatic tumor and enter the blood circulation is called CTCs.It is crucial to develo...