Onchocerciasis-associated epilepsy:another piece in the puzzle from the Mahenge mountains, southern Tanzania  

作　　者：Christoph Kaiser Bruno P.Mmbando Joseph N.Siewe Fodjo Patrick Suykerbuyk Mohamed Mnacho Advocatus Kakorozya William Matuja Adam Hendy Helena Greter Williams H.Makunde Robert Colebunders 

机构地区：[1]Pediatric Practice,Balzenbergstrasse 73,76530 Baden-Baden,Germany [2]National Institute for Medical Research,Tanga Research Centre,Tanga,Tanzania [3]Global Health Institute,University of Antwerp,Antwerp,Belgium [4]Muhimbili National Hospital,Dar es Salaam,Tanzania [5]Enhance Tanzania Foundation,Dar es Salaam,Tanzania [6]Muhimbili University of Health and allied Sciences,Dar es Salaam,Tanzania [7]University of Texas Medical Branch,Galveston,TX,USA

出　　处：《Infectious Diseases of Poverty》2019年第3期88-93,共6页贫困所致传染病（英文）

摘　　要：In a study from the onchocerciasis-endemic area of Mahenge in southern Tanzania,Mmbando et al.[Inf Dis Poverty.2018,7:64]demonstrate that in four selected villages the overall epilepsy prevalence was high,and significantly more elevated in the two villages of higher onchocerciasis endemicity compared to those of lower endemicity.This is replicating earlier findings from many other areas of tropical Africa.The authors are also providing data indicating that in the Mahenge focus,the prevalence of nodding syndrome may be related to that of onchocerciasis in the same way as epilepsy in general.The application of a clinical case definition for onchocerciasis-associated epilepsy(OAE)as used in the study of Mmbando et al.[Inf Dis Poverty.2018;7:64]faces some difficulties;indeed,its precision in discerning cases of OAE from epilepsy due to other etiologies is not known,and it does not allow for a specific diagnosis in the individual patient.Because an operational surveillance tool for assessing the number of patients in the population could mean substantial advance for better estimating the burden of OAE,the proposed definition should be tried in different settings and its performance reviewed in the process.

关 键 词：EPILEPSY MOUNTAINS POVERTY 

分 类 号：R74[医药卫生—神经病学与精神病学]