低剂量胸部CT筛查早期肺癌的临床应用研究  

Clinical study of low-dose chest CT plain scan in screening early lung cancer

作　　者：王利平[1] 段颖佳 候箭[1] 翟福林[1] WANG Liping;DUAN Yingjia;HOU Jian;ZHAI Fulin(Department of Oncology,the First People's Hospital of Chenzhou City,Hunan Chenzhou 423000,China)

机构地区：[1]郴州市第一人民医院肿瘤内科,湖南郴州423000

出　　处：《现代肿瘤医学》2021年第3期407-409,共3页Journal of Modern Oncology

基　　金：湖南省科技创新计划项目(编号:2018JJ3016);湘南学院课题项目(编号:2016XJ63)。

摘　　要：目的:探讨低剂量CT(low-dose chest CT,LDCT)胸部平扫在健康体检中筛查早期肺癌的应用效果及价值。方法:收集2018年1月至2018年12月在我院健康体检高危人群,采用低剂量胸部CT 1 100例及胸部X线平片750例。结果:低剂量胸部CT与胸部X线片比较,发现肺结节病灶,阳性肺结节以及疑似肺癌的比例均具有统计学意义(P<0.05);低剂量CT组确诊为肺癌的患者,腺癌占比90%,女性肺癌占比40%,男性肺癌占比60%,50岁以上肺癌占比60%,基因检测结果提示驱动基因阳性占比42.5%。结论:低剂量CT胸部检查与胸片比较,恶性肿瘤检出率高,是一种适用于肺癌的早期筛查方法。Objective:To explore the application effect and value of low-dose CT(LDCT)chest plain scan in screening early lung cancer in physical examination.Methods:1100 cases of low-dose chest CT and 750 cases of chest X-ray irradiation were collected from January to December 2018 in our hospital.Results:Compared with chest X-ray,low-dose chest CT showed that the proportion of pulmonary nodule focus,positive pulmonary nodule and diagnosed lung cancer was statistically significant(P<0.05).In the low-dose CT group,the proportion of patients with lung adenocarcinoma was 90%,accounts for 40%in women,60%in men,60%in patients over 50 years old and 42.5%of them were positive for driving gene.Conclusion:Compared with chest radiograph,low-dose CT has a high detection rate of malignant tumor,which is an early screening method for lung cancer.

关 键 词：低剂量胸部CT 肺癌 基因检测 

分 类 号：R734.2[医药卫生—肿瘤]