Adult neurogenesis: Is it showtime for clinical translation?  

作　　者：Yu-Jie Lai Fei Sun Guo-Jun Chen 

机构地区：[1]Department of Neurology,The First Affiliated Hospital,Chongqing Medical University,and The Chongqing Key Laboratory of Neurology,Chongqing 400016,China [2]Department of Physiology,Wayne State University School of Medicine,Detroit,Ml 48201,USA

出　　处：《Genes & Diseases》2015年第4期291-292,共2页基因与疾病（英文）

基　　金：This work was supported by NSFC grants(81220108010 and 81171197)to GC and a NIH grant(HL096800)to FS.

摘　　要：The existence of adult stem cells was first described in tissues with high proliferation rates,such as the hematopoietic system and the intestine.Since then,stem cells have been found in almost all adult tissues,including the nervous system.Adult neurogenesis is supported by multipotent neural stem cells(NSCs),which maintain some of the cellular and molecular characteristics of their embryonic counterparts.Because of their suggestive appeal as therapeutic agents and their presumed relevance for cognition in health and disease,adult neurogenesis is attracting considerable attention from neuroscientists.

关 键 词：Adult neurogenesis ASTROGLIA B1 cells Multipotent neural stem cells(NSCs) Neurological disorders 

分 类 号：R73[医药卫生—肿瘤]