Helicobacter pylori:Commensal,symbiont or pathogen?  被引量:12

在线阅读下载全文

作  者:Vasiliy Ivanovich Reshetnyak Alexandr Igorevich Burmistrov Igor Veniaminovich Maev 

机构地区:[1]Department of Propaedeutic of Internal Diseases and Gastroenterology,A.I.Yevdokimov Moscow State University of Medicine and Dentistry,Moscow 127473,Russia

出  处:《World Journal of Gastroenterology》2021年第7期545-560,共16页世界胃肠病学杂志(英文版)

摘  要:This review considers the data on Helicobacter pylori(H.pylori),which have been accumulated over 40 years since its description as an etiological factor in gastrointestinal diseases.The majority of modern publications are devoted to the study of the pathogenic properties of the microorganism in the development of chronic gastritis,peptic ulcer disease,and gastric cancer,as well as methods for its eradication.However,in recent years,there have been more and more studies which have suggested that H.pylori has a beneficial,or potentially positive,effect on the human body.The authors have attempted to objectively analyze the information accumulated in the literature on H.pylori.Some studies consider it as one of the recently identified human bacterial pathogens,and special attention is paid to the evidence suggesting that it is probably part of the composition of the human microbiome as a commensal(commensal from French to English is a table companion)or even a symbiont.The presented data discussing the presence or absence of the effect of H.pylori on human health suggest that there is an apparent ambiguity of the problem.The re-assessment of the data available on H.pylori infection is important in order to answer the question of whether it is necessary to create a program of mass H.pylori eradication or to apply a more personalized approach to treating patients with H.pylori-associated gastrointestinal diseases and to perform eradication therapy.

关 键 词:Helicobacter pylori PATHOGEN COMMENSAL MICROBIOME Peptic ulcer Gastric cancer ASTHMA Inflammatory bowel diseases 

分 类 号:R57[医药卫生—消化系统]

 

参考文献:

正在载入数据...

 

二级参考文献:

正在载入数据...

 

耦合文献:

正在载入数据...

 

引证文献:

正在载入数据...

 

二级引证文献:

正在载入数据...

 

同被引文献:

正在载入数据...

 

相关期刊文献:

正在载入数据...

相关的主题
相关的作者对象
相关的机构对象