矿质离子螯合肽自组装递送体系研究进展  

Research progress of self-assembly delivery system of mineral ion chelating peptide

作　　者：尹乐斌 廖聪 刘丹 杨爱莲 刘桠丽 何平 李乐乐 YIN Lebin;LIAO Cong;LIU Dan;YANG Ailian;LIU Yali;HE Ping;LI Lele(College of Food and Chemical Engineering,Shaoyang University,Shaoyang 422000,China;Hunan Provincial Key Laboratory of Soybean Products Processing and Safety Control,Shaoyang 422000,China)

机构地区：[1]邵阳学院食品与化学工程学院,湖南邵阳422000 [2]豆制品加工与安全控制湖南省重点实验室,湖南邵阳422000

出　　处：《食品与发酵工业》2021年第5期296-302,共7页Food and Fermentation Industries

基　　金：湖南省科技计划项目“湖湘青年英才”(2016RS3035);湖南省教育厅优秀青年项目(18B427);湖南省研究生科研创新项目(CX20190971);邵阳学院“双一流”建设产学研合作平台(邵院通[2018]50号)。

摘　　要：钙、铁、锌、硒、铜、铬等矿质元素与人体生长、发育、繁殖、代谢等生命活动密切相关,多肽与矿质离子间可自发组织或聚集成具有稳定结构的有机螯合物,这一类新型补充剂在稳定性、促吸收、生理活性等方面比以往的金属离子补充剂更具优势。该文阐述了多肽-矿质离子螯合物来源及制备、自组装模式、促生物利用度,并对多肽-矿质离子螯合物及其多元超分子自组装递送体系前景进行了展望。Some mineral elements,such as calcium,iron,zinc,selenium,copper and chromium are closely related to human growth,development,reproduction,metabolism et al.Peptides and mineral elements can organize spontaneously or aggregate into mineral-organic chelate with a stable structure.This type of replenishers have more advantages than previous metal ions supplements in terms of stability,absorption promotion,and physiological activity.This article described the source and preparation,self-assembly mode,and bio-availability of the peptide-mineral ion chelate.Furthermore,the peptide-mineral chelates and their multiple supra-molecular self-assembly delivery systems were also been prospected.

关 键 词：多肽 矿质离子 自组装 生理活性 促吸收 

分 类 号：TS201.2[轻工技术与工程—食品科学]