食品中重金属的人体健康风险评估方法研究进展  

Human health risk assessment of heavy metals in food:a review

作　　者：李梦莹[1] 王成尘 毕珏 覃一书 王坤 向萍 LI Mengying;WANG Chengchen;BI Jue;QIN Yishu;WANG Kun;XANG Ping(School of Ecology and Environment,Southwest Forestry University,Kunming,Yunnan 650224,China)

机构地区：[1]西南林业大学生态与环境学院,云南昆明650224

出　　处：《福建农林大学学报（自然科学版）》2021年第1期1-9,共9页Journal of Fujian Agriculture and Forestry University:Natural Science Edition

基　　金：国家自然科学基金资助项目(41967026);云南省创新团队项目(202005AE160017);云南农业基础研究联合专项面上项目(2018FG001-048);国家林业和草原局林草科技创新青年拔尖人才项目(2020132613);云南省高层次人才引进计划青年人才项目(YNQR-QNRC-2018-049)。

摘　　要：食品安全是一个关乎全球可持续发展的重要问题.近几十年来,环境中的重金属对食品质量的不良影响已经威胁到人类,运用模型评估食品中的重金属对人体健康的危害程度是必然趋势.目前研究人员常用的方法主要是评价公式、体外消化系统模拟实验、动物模型实验和肠道细胞模型实验,本文总结了4种常用方法的优势和局限性并进行了讨论.在未来,体外和体内方法相辅相成能更准确地评估食品中的重金属对人体健康的危害.Food safety is an important issue related to global sustainable development.In recent decades,the adverse effects of heavy metals from the environment on food quality have threatened human beings.It is an inevitable trend to use models to evaluate the harmfulness of food-derived heavy metals to human health.The commonly used assessment methods are summarized in this review,which include evaluation formulas,in vitro digestive system simulation test,animal model and intestinal cell model.The advantages and disadvantages of the 4 methods were summarized and discussed.The review proposes that the combination of in vitro and in vivo methods can more accurately evaluate the harmfulness of heavy metals in food upon human health.

关 键 词：食品 重金属 人体健康风险评估 

分 类 号：R155.5[医药卫生—营养与食品卫生学]