Insight into the roles of long non-coding RNAs in ultraviolet-induced skin diseases  

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作  者:Yu-Jia Wang Xian Jiang 

机构地区:[1]Department of Dermatology,State Key Laboratory of Biotherapy,West China Hospital,Sichuan University,Chengdu,Sichuan 610041,China

出  处:《Chinese Medical Journal》2021年第4期398-400,共3页中华医学杂志(英文版)

基  金:This research was supported by a grant from the National Natural Science Foundation of China(No.81872535)。

摘  要:Long non-coding RNAs(LncRNAs)comprise different types of RNA polymerase II-transcripted molecules,exhibit nucleotide lengths of greater than 200 nucleotides and do not undergo protein translation.Due to their characteristic feature of open reading frame,they have often been labelled as the"noise"of genomic transcription.Even though lncRNAs are widely transcribed genes,their expression level is lower than that of the protein-coding genes.Depending on their position relative to the protein-coding genes in the genome,lncRNAs are categorized as sense,antisense,bidirectional,intronic,and intergenic.

关 键 词:DISEASES ULTRAVIOLET RNAS 

分 类 号:R751[医药卫生—皮肤病学与性病学]

 

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