RNAS

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相关机构：浙江大学华中科技大学山东大学北京协和医学院更多>>
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扩展青霉孢子及菌丝中环状RNAs的比较分析
《杭州师范大学学报(自然科学版)》2025年第2期181-189,196,共10页章鹏程 王菲 杨倩 柏张奕 于春雨 周婷 
浙江省自然科学基金杭州区域创新发展联合基金资助项目(LHZY24C140001).
利用高通量测序和生物信息学分析技术对扩展青霉孢子和菌丝的环状RNAs进行了鉴定,对其碱基组成、种类、染色体定位和表达量进行了比较分析,对差异表达环状RNAs的来源基因进行了GeneOntology(GO)和KyotoEncyclopediaofGenesandGenomes(KE...
关键词：扩展青霉 环状RNAs 孢子 菌丝 
Circulating circular RNAs act as potential novel biomarkers for sepsis secondary to pneumonia:a prospective cohort study
《World Journal of Emergency Medicine》2025年第2期144-152,共9页Chunxue Wang Dianyin Yang Yuxin Zhu Qian Yang Tong Liu Xiandong Liu Dongyang Zhao Xiaowei Bao Tiancao Dong Li Shao Lunxian Tang 
supported by grants from the municipal Natural Science Foundation of Shanghai Scientific Committee of China(22ZR1451000 to TL);the peak supporting clinical discipline of Shanghai Health Bureau(2023ZDFC0104 to TL);the key clinical discipline of Shanghai Pudong Health Bureau(PWZxk2022-17 to TL);the clinical peak discipline of Shanghai Pudong Heath Bureau(PWYgf2021-03);the top-notch innovative medical talents of Shanghai Pudong Health Bureau(2025PDWSYCBJ-03 to TL);the leading medical talent project of Shanghai Pudong Heath Bureau(PWR12020-07 to LS)。
BACKGROUND:Circulating biomarkers for sepsis are lacking,and research on circular RNAs(circR NAs)as potential biomarkers of pneumonia-induced sepsis is limited.This study aims to investigate the diagnostic and prognos...
关键词：Circular RNAs BIOMARKER Pneumonia-induced sepsis Diagnosis Prognosis 
Circular RNA contributes to gastric cancer by targeting Wnt family member 2B as a competing endogenous RNA
《World Journal of Gastroenterology》2025年第10期71-85,共15页Wei Bai Zong-Liang Guo Jiang-Hong Guo Feng Li Peng Bu Juan Liu 
BACKGROUND As a non-coding RNA molecule,circular RNAs(circRNAs)have significant specificity,and existing data suggest a close relationship between them and the prognosis of patients with gastric cancer(GC).However,thi...
关键词：Competing endogenous RNA Wnt family member 2B MicroRNA-4529-5p Circular RNAs Gastric cancer 
Oxidative stress-induced circSOD2 inhibits osteogenesis through sponging miR-29b in metabolic-associated fatty liver disease
《World Journal of Gastroenterology》2025年第9期68-82,共15页Liang-Ping Li Xiao-Ying Chen Hong-Bo Liu Yi Zhu Min-Jie Xie Yong-Jian Li Meng Luo Mugahed Albahde Hong-Yu Zhang Jian-Ying Lou 
Supported by the National and Zhejiang Provincial Administration of Traditional Chinese Medicine Co-construction Project,No.GZYZJ-KJ-24080;the Medical Science and Technology Project of Zhejiang Province,No.2024XY228.
BACKGROUND Metabolic-associated fatty liver disease(MAFLD)is characterized by lipid accumulation in hepatocytes and is closely associated with oxidative stress.Increasing clinical evidence indicates that MAFLD is link...
关键词：Circular RNAs MICRORNAS Oxidative stress OSTEOGENESIS Non-alcoholic fatty liver disease OSTEOPOROSIS 
Decoding the intracellular trafficking rule for circular RNAs
《Science China(Life Sciences)》2025年第2期590-592,共3页Jiao Li Xiaojuan Yang Yong Peng 
supported by the National Natural Science Foundation of China(82273168);the 1.3.5 Project for Disciplines of Excellence,West China Hospital of Sichuan University(ZYGD23027)。
Circular RNAs(circRNAs)are endogenous single-stranded RNAs with a covalently closed loop generated from'backsplicing'of precursor mRNA(pre-mRNA)in the nucleus.Mounting evidence emphasizes their significance in cellula...
关键词：ENDOGENOUS HOMEOSTASIS DISEASES 
Long non-coding RNAs as promising targets for controlling disease vector mosquitoes
《Insect Science》2025年第1期24-41,共18页Yujiao Han Qian Pu Ting Fan Tianqi Wei Yankun Xu Lu Zhao Shiping Liu 
supported by the National Natural Science Foundation of China(32172797);Chongqing Science and Technology Plan Project(2022NSCQMSX5897);Chongqing Graduate Student Research Innovation Project(CYB21132,CYS22254 and CYS23241);Fundamental Research Funds for the Central Universities(SWU-XJPY202309).
Hematophagous female mosquitoes are important vectors of numerous devastating human diseases,posing a major public health threat.Effective prevention and control of mosquito-borne diseases rely considerably on progres...
关键词：competitive endogenous RNAs(ceRNAs) insecticide resistance long noncoding RNA(lncRNA) MOSQUITO mosquito-borne diseases pathogen-host interaction 
Genome-wide circular RNAs signatures involved in sexual maturation and its heterosis in chicken
《Journal of Integrative Agriculture》2025年第2期697-711,共15页Yuanmei Wang Jingwei Yuan Yanyan Sun Aixin Ni Jinmeng Zhao Yunlei Li Panlin Wang Lei Shi Yunhe Zong Pingzhuang Ge Shixiong Bian Hui Ma Jilan Chen 
funded by the National Natural Science Foundation of China(32172721);the China Agriculture Research System(CARS-40);the Central Publicinterest Scientific Institution Basal Research Fund,China(2021-YWF-ZYSQ-12);the Agricultural Science and Technology Innovation Program of Chinese Academy of Agricultural Sciences(ASTIP-IAS04)。
Sexual maturation heterosis has been widely exploited in animal crossbreeding.However,the underlying mechanism has been rarely explored in chicken.In the present study,we performed the reciprocal crossing between Whit...
关键词：CHICKEN sexual maturation HETEROSIS OVARY circRNA 
Unraveling the role of long non‑coding RNAs in chronic heat stress‑induced muscle injury in broilers
《Journal of Animal Science and Biotechnology》2025年第1期206-217,共12页Zhen Liu Yingsen Liu Tong Xing Jiaolong Li Lin Zhang Liang Zhao Yun Jiang Feng Gao 
National Natural Science Foundation of China(32072780,31872374);National Key Research and Development Program of China(2016YFD0500501,2018YFD0500405);Earmarked Fund for Jiangsu Agricultural Industry Technology System(JATS[2024]).
Background Chronic heat stress(CHS)is a detrimental environmental stressor with a negative impact on the meat quality of broilers.However,the underlying mechanisms are not fully understood.This study investigates the ...
关键词：Apoptosis BROILER Chronic heat stress LncRNA MUSCLE 
Profiling and bioinformatics analyses of circular RNAs in myocardial ischemia/reperfusion injury model in mice
《World Journal of Cardiology》2025年第1期65-77,共13页Jiao-Ni Wang Ying-Ying Zhou Yong-Wei Yu Jun Chen 
Supported by Zhejiang Provincial Natural Science Foundation of China,No.LQ23H020004;The Medical and Health Research Project of Zhejiang province,No.2024KY983;Basic Medical Health Technology Project of Wenzhou Science and Technology Bureau,No.Y20210818 and No.Y20210140.
BACKGROUND Myocardial ischemia/reperfusion(I/R)injury,which is associated with high morbidity and mortality,is a main cause of unexpected myocardial injury after acute myocardial infarction.However,the underlying mech...
关键词：Rna-sequencing Circular RNA MicroRNA CeRNA Myocardial ischemia/reperfusion Bioinformatics analyses 
Non-coding RNAs in acute ischemic stroke:from brain to periphery
《Neural Regeneration Research》2025年第1期116-129,共14页Shuo Li Zhaohan Xu Shiyao Zhang Huiling Sun Xiaodan Qin Lin Zhu Teng Jiang Junshan Zhou Fuling Yan Qiwen Deng 
supported by the National Natural Science Foundation of China,Nos.82301486(to SL)and 82071325(to FY);Medjaden Academy&Research Foundation for Young Scientists,No.MJR202310040(to SL);Nanjing Medical University Science and Technique Development,No.NMUB20220060(to SL);Medical Scientific Research Project of Jiangsu Commission of Health,No.ZDA2020019(to JZ);Health China Buchang Zhiyuan Public Welfare Project for Heart and Brain Health,No.HIGHER202102(to QD).
Acute ischemic stroke is a clinical emergency and a condition with high morbidity,mortality,and disability.Accurate predictive,diagnostic,and prognostic biomarkers and effective therapeutic targets for acute ischemic ...
关键词：acute ischemic stroke apoptosis blood–brain barrier damage circular RNAs excitatory toxicity long non-coding RNAs MICRORNAS NEUROINFLAMMATION non-coding RNAs oxidative stress 
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