RNAS

作品数：491被引量：1687H指数：16
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相关机构：浙江大学华中科技大学山东大学北京协和医学院更多>>
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Landscape of chimeric RNAs in COVID-19 patient blood
《Genes & Diseases》2025年第3期599-610,共12页Samuel Haddox Ping Wu Sandeep Singh Fujun Qin Jack Engel Andrea Kian Syed Ahmad Hui Li Peng Wu 
supported by the National Institutes of Health(USA)(No.R01GM132138 to H.L.).
Despite the availability of efficacious vaccines, COVID-19 persists and our knowledge of how SARS-CoV-2 infection affects host transcriptomics remains incomplete. Transcriptome analysis, which has progressed our under...
关键词：BLOOD Chimeric RNA COVID-19 PTBP1 SARS-CoV-2 
Non-coding RNAs in adipose-derived stem cell exosomes:Mechanisms,therapeutic potential,and challenges in wound healing
《World Journal of Stem Cells》2025年第4期6-19,共14页Jian Rong Yao-Yao Li Xin Wang Jia-Ning Wang Mei Song 
Supported by the Intra-Hospital Project of No.940 Hospital of the Joint Logistics Support Force of the Chinese People’s Liberation Army,No.2021yxky016.
The treatment of complex wounds presents a significant clinical challenge due to the limited availability of standardized therapeutic options.Adipose-derived stem cell exosomes(ADSC-Exos)are promising for their capabi...
关键词：Adipose-derived stem cell exosomes Wound healing MICRORNAS Long noncoding RNAs Circular RNAs 
扩展青霉孢子及菌丝中环状RNAs的比较分析
《杭州师范大学学报(自然科学版)》2025年第2期181-189,196,共10页章鹏程 王菲 杨倩 柏张奕 于春雨 周婷 
浙江省自然科学基金杭州区域创新发展联合基金资助项目(LHZY24C140001).
利用高通量测序和生物信息学分析技术对扩展青霉孢子和菌丝的环状RNAs进行了鉴定,对其碱基组成、种类、染色体定位和表达量进行了比较分析,对差异表达环状RNAs的来源基因进行了GeneOntology(GO)和KyotoEncyclopediaofGenesandGenomes(KE...
关键词：扩展青霉 环状RNAs 孢子 菌丝 
Circulating circular RNAs act as potential novel biomarkers for sepsis secondary to pneumonia:a prospective cohort study
《World Journal of Emergency Medicine》2025年第2期144-152,共9页Chunxue Wang Dianyin Yang Yuxin Zhu Qian Yang Tong Liu Xiandong Liu Dongyang Zhao Xiaowei Bao Tiancao Dong Li Shao Lunxian Tang 
supported by grants from the municipal Natural Science Foundation of Shanghai Scientific Committee of China(22ZR1451000 to TL);the peak supporting clinical discipline of Shanghai Health Bureau(2023ZDFC0104 to TL);the key clinical discipline of Shanghai Pudong Health Bureau(PWZxk2022-17 to TL);the clinical peak discipline of Shanghai Pudong Heath Bureau(PWYgf2021-03);the top-notch innovative medical talents of Shanghai Pudong Health Bureau(2025PDWSYCBJ-03 to TL);the leading medical talent project of Shanghai Pudong Heath Bureau(PWR12020-07 to LS)。
BACKGROUND:Circulating biomarkers for sepsis are lacking,and research on circular RNAs(circR NAs)as potential biomarkers of pneumonia-induced sepsis is limited.This study aims to investigate the diagnostic and prognos...
关键词：Circular RNAs BIOMARKER Pneumonia-induced sepsis Diagnosis Prognosis 
The discovery of tiny RNAs that have crucial roles
《Science China(Life Sciences)》2025年第4期1183-1185,共3页Shouhong Guang Mo-Fang Liu 
On October 7, the Nobel Assembly at Sweden's Karolinska Institute announced the awarding of the 2024 Nobel Prize in Physiology or Medicine to American scientists Victor Ambros and Gary Ruvkun for their discovery of mi...
关键词：tiny RNAs MICRORNAS posttranscriptional gene regulation nobel assembly 
Expression profiling and bioinformatics analysis of serum exosomal circular RNAs in lymph node metastasis of papillary thyroid carcinoma
《Journal of Biomedical Research》2025年第2期155-170,I0001-I0004,共20页Huiyong Peng Zhangwei Zhu Jie Xing Qian Xu Changfeng Man Shengjun Wang Yingzhao Liu Zhengdong Zhang 
National Natural Science Foundation of China (Grant No. 81800698);Jiangsu Provincial Medical Key Discipline Cultivation Unit (Grant No. JSDW202241);Research Project of Jiangsu Commission of Health (Grant No. H2023053);Zhenjiang Science and the Technology Planning Project (Grant Nos. SH2023006and SH2023008)。
Most papillary thyroid carcinoma(PTC) patients have a good prognosis. However, lymph node metastasis(LNM), the most common manifestation of disease progression, is frequently associated with a poor prognosis.Neverthel...
关键词：papillary thyroid carcinoma EXOSOME circular RNA regulatory network lymph node metastasis 
Peri-centrosomal localization of small interfering RNAs in C.elegans
《Science China(Life Sciences)》2025年第4期895-911,共17页Qile Jin Xuezhu Feng Minjie Hong Ke Wang Xiangyang Chen Jiewei Cheng Yan Kuang Xiaoyue Si Mingjing Xu Xinya Huang Shouhong Guang Chengming Zhu 
funded by the National Institutes of Health(NIH)Office of Research Infrastructure Programs(P40 OD010440);supported by grants from the National Natural Science Foundation of China(32230016 awarded to S.G.,32270583 awarded to C.Z.,32070619 awarded to X.F.,2023M733425 awarded to X.H.,and 32300438 awarded to X.H.);the National Key R&D Program of China(2022YFA1302700 to S.G.);the Research Funds of Center for Advanced Interdisciplinary Science and Biomedicine of IHM(QYPY20230021 awarded to S.G.);the Fundamental Research Funds for the Central Universities。
The centrosome is the microtubule-organizing center and a crucial part of cell division.Centrosomal RNAs(cnRNAs)have been reported to enable precise spatiotemporal control of gene expression during cell division in ma...
关键词：SIRNA centrosomal RNAs NRDE-3 
氡温泉周围居民外周血circRNAs表达分析
《中华放射医学与防护杂志》2025年第3期178-182,共5页张佳 阮健磊 李小亮 刘建香 
目的分析氡温泉对其周围居民外周血环状RNAs(circRNAs)表达的影响。方法选取四川省某氡温泉周围居民51人作为氡温泉组,选取非氡温泉周围居民51人作为对照组。通过问卷调查收集两组研究对象的人口统计学资料及居民氡暴露程度的资料,实时...
关键词：氡温泉 外周血 环状RNAs 累积剂量 
Circular RNA contributes to gastric cancer by targeting Wnt family member 2B as a competing endogenous RNA
《World Journal of Gastroenterology》2025年第10期71-85,共15页Wei Bai Zong-Liang Guo Jiang-Hong Guo Feng Li Peng Bu Juan Liu 
BACKGROUND As a non-coding RNA molecule,circular RNAs(circRNAs)have significant specificity,and existing data suggest a close relationship between them and the prognosis of patients with gastric cancer(GC).However,thi...
关键词：Competing endogenous RNA Wnt family member 2B MicroRNA-4529-5p Circular RNAs Gastric cancer 
Oxidative stress-induced circSOD2 inhibits osteogenesis through sponging miR-29b in metabolic-associated fatty liver disease
《World Journal of Gastroenterology》2025年第9期68-82,共15页Liang-Ping Li Xiao-Ying Chen Hong-Bo Liu Yi Zhu Min-Jie Xie Yong-Jian Li Meng Luo Mugahed Albahde Hong-Yu Zhang Jian-Ying Lou 
Supported by the National and Zhejiang Provincial Administration of Traditional Chinese Medicine Co-construction Project,No.GZYZJ-KJ-24080;the Medical Science and Technology Project of Zhejiang Province,No.2024XY228.
BACKGROUND Metabolic-associated fatty liver disease(MAFLD)is characterized by lipid accumulation in hepatocytes and is closely associated with oxidative stress.Increasing clinical evidence indicates that MAFLD is link...
关键词：Circular RNAs MICRORNAS Oxidative stress OSTEOGENESIS Non-alcoholic fatty liver disease OSTEOPOROSIS 
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