微信群延续性指导模式对婴儿痉挛症患儿生酮饮食保留率的影响  

The effect of the mode of continuous guidance with wechat group on the ketogenic diet retention rate in children with infantile spasms

作　　者：查剑[1] 曹芳芳 熊玲[1] 方菊花 易招师[1] 杨倩倩 陈勇[1] 钟建民[1] ZHA Jian;CAO Fangfang;XIONG Ling;FANG Juhua;YI Zhaoshi;YANG Qianqian;CHEN Yong;ZHONG Jianmin(Department of Neurology,Jiangxi Provincial Children's Hospital(The Affiliated Children's Hospital of Nanchang University),Nanchang 330006,China)

机构地区：[1]江西省儿童医院(南昌大学附属儿童医院)神经内科,南昌330006

出　　处：《癫痫杂志》2021年第2期122-126,共5页Journal of Epilepsy

基　　金：江西省卫生健康委员会科技计划资金资助项目(20203675)。

摘　　要：目的探讨微信群延续性指导模式在生酮饮食(Ketogenic Diet,KD)治疗婴儿痉挛症(Infantile Spasms,IS)中对治疗保留率及有效率的影响。方法回顾性分析2017年1月—2019年6月于江西省儿童医院进行KD治疗的40例IS患儿病例资料,其中男23例,女17例,平均年龄(19.90±13.10)月龄,平均病程(9.95±7.61)个月,随机分为对照组(20例)及观察组(即微信群延续性指导组20例),并随访1年,比较两组的保留率及疗效。结果观察组及对照组的一般资料比较,差异无统计学意义(P>0.05),具有可比性。在KD治疗9、12个月时,观察组的保留率显著高于对照组(P均<0.05),有效率亦显著高于对照组(P均<0.05),且无发作率较对照组显著增高(35%vs.10%,35%vs.15%)。结论微信群延续性指导模式可增加IS患儿的KD治疗长期保留率,从而增加其治疗的有效率。Objective To explore the impact on the retention and effective rate of the mode of continuous guidance with wechat group in children with infantile spasms(IS)treated by ketogenic diet(KD).Methods The clinical data of 40 children who received KD treatment in Jiangxi Children’s Hospital from January 2017 to June 2019 were retrospectively analyzed,including 23 males and 17 females,the average age was(19.90±13.10)months and the average course was(9.95±7.61)months.They were randomly divided into control group(20 cases)and observation group(wechat group continuity Guidance Group,20 cases),and followed up one year to compare the retention rate and efficacy.Results There was no statistical difference between the general data of the observation group and the control group(P>0.05).After 9 and 12 months of KD treatment,the retention and effective rate of the observation group was significantly higher than the control group(P<0.05).And the seizure-free rate was higher than the control group(35%vs.10%,35%vs.15%).Conclusion This model of continuous guidance with wechat group can increase the KD retention rate of IS children,And increase the effective rate.

关 键 词：生酮饮食 婴儿痉挛症 微信 保留率 疗效 

分 类 号：R742.1[医药卫生—神经病学与精神病学]