Caspase-1:an important player and possible target for repair of the blood-brain barrier underlying neurodegeneration  

作　　者：Daniel Rand Itzik Cooper 

机构地区：[1]The Joseph Sagol Neuroscience Center,Sheba Medical Center,Ramat-Gan,Israel [2]Sackler Faculty of Medicine,Tel-Aviv University,Tel Aviv,Israel [3]School of Psychology,Interdisciplinary Center(IDC),Herzliya,Israel [4]The Nehemia Rubin Excellence in Biomedical Research-The TELEM Program,Sheba Medical Center,Tel-Hashomer,Israel

出　　处：《Neural Regeneration Research》2021年第12期2390-2392,共3页中国神经再生研究（英文版）

基　　金：This work was supported by the Defense Threat Reduction Agency-Joint Science&Technology Office for Chemical&Biological Defense(No.11816372);the Nehemia Rubin Excellence in Biomedical Research-The TELEM Program supported by the Aaron Gutwirth Fund and by Ministry of Science and Technology(No.3-13576).

摘　　要：Our ageing population is bearing an increasing burden on society with an unprecedented rise in brain disease,especially neurodegeneration.Treatment for neurodegeneration is practically nonexistent,one major reason being the bloodbrain barrier(BBB).The BBB is a crucial component in maintaining a healthy brain as it protects the brain from the entrance of toxins and removes them from the brain’s vicinity,providing proper clearance.

关 键 词：NEURODEGENERATION BARRIER REMOVE 

分 类 号：R741[医药卫生—神经病学与精神病学]