树脂催化合成没食子酸丙酯及工艺优化  

Synthesis of Propyl Gallate Catalyzed by Resin and Process Optimization

作　　者：董刚 刘兰香[1] 孙彦琳[2] 李坤[1] 张雯雯[1] 刘义稳 陈清龙 张弘[1] Dong Gang;Liu Lanxiang;Sun Yanlin;Li Kun;Zhang Wenwen;Liu Yiwen;Chen Qinglong;Zhang Hong(Research Institute of Resources Insects,Chinese Academy of Forestry,Research Center of Engineering and Technology on Characteristic Forest Resources,State Administration of Forestry and Grassland,Kunming 650223,China;College of Chemical Engineering,Kunming University of Science and Technology,Kunming 650500,China;Wufeng Chicheng Biotechnology CO.,LTD.,Research Center of Engineering and Technology on Efficient Cultivation and Intensive Processing for Gallnut of Forestry and Grassland Administration of China,Hubei Yichang 443413,China)

机构地区：[1]中国林业科学研究院资源昆虫研究所,国家林业和草原局特色森林资源工程技术研究中心,昆明650223 [2]昆明理工大学化学工程学院,昆明650500 [3]五峰赤诚生物科技股份有限公司,国家林业和草原局五倍子高效培育与精深加工工程技术研究中心,湖北宜昌443413

出　　处：《化学工业与工程》2021年第1期27-35,共9页Chemical Industry and Engineering

基　　金：国家重点研发计划(2018YFD0600404)。

摘　　要：阳离子交换树脂作为非均相催化剂的一种,大量应用于有机合成反应中。通过筛选树脂种类、活化酸类型、活化酸浓度等制备高活性树脂催化剂,用于非均相催化合成没食子酸丙酯。结果表明:当A-15树脂经盐酸活化后可高效催化合成没食子酸丙酯,其用量为反应原料总质量的4.06%,反应20 h时,收率稳定在91.0%左右,通过高效液相色谱法测得没食子酸丙酯的纯度大于99.9%。该树脂催化剂通过再生可重复使用40次以上,催化剂可回收循环利用,解决了酸排放量的问题,与传统浓硫酸催化法相比,能满足催化效率高、绿色环保、经济的新型工业要求。As a heterogeneous catalyst,cation exchange resins are widely used in organic synthesis reactions.Preparation of highly active resin catalysts for the synthesis of propyl gallate by screening of resin types,activated acid types,activated acid concentration,etc.The results showed that when the resin catalyst dosage was 4.06%of the total mass of the reaction raw materials,the reaction time was 20 h,the yield of propyl gallate was stable at about 91.0%,and the purity of propyl gallate was greater than 99.9%that measured by high performance liquid phase.The resin catalyst could be reused more than 40 times through regeneration,and its effectively reduced the problem of solving acid discharge.Compared with traditional methods,the method in this paper could better meet the new industrial requirements of high catalytic efficiency,environmental protection and economy.

关 键 词：树脂 催化剂 非均相 合成 没食子酸丙酯 

分 类 号：TQ426.7[化学工程] TS202.3[轻工技术与工程—食品科学]