Burden of atrial fibrillation in patients with rheumatic diseases  

作　　者：Muhammad Zubair Khan Kirtenkumar Patel Krunalkumar A Patel Rajkumar Doshi Vraj Shah Devina Adalja Zainulabedin Waqar Sona Franklin Neelesh Gupta Muhammad Hamdan Gul Shruti Jesani Steven Kutalek Vincent Figueredo 

机构地区：[1]Department of Internal Medicine,St.Mary Medical Center,Langhorne,PA 19047,United States [2]Division of Cardiology,North Shore University Hospital,Manhasset,NY 11030,United States [3]Department of Internal Medicine,University of Nevada Reno School of Medicine,Reno,NV 89502,United States [4]Division of Cardiology,Medical College of Baroda,Baroda 390001,India [5]Department of Internal Medicine,GMERS Gotri Medical College,Vadodara 390021,India [6]Department of Internal Medicine,Mercy St.Vincent Medical Center,Toledo,OH 43608,United States [7]Department of Internal Medicine,Nazareth Hospital,Philadelphia,PA 19115,United States [8]Department of Internal Medicine,Saint Joseph Hospital,Chicago,IL 60657,United States [9]Department of Internal Medicine,Trinitas Regional Medical Center,Elizabeth,NJ 07202,United States [10]Department of Cardiology,St.Mary Medical Center,Langhorne,PA 19047,United States

出　　处：《World Journal of Clinical Cases》2021年第14期3252-3264,共13页世界临床病例杂志

摘　　要：BACKGROUND Studies have suggested that atrial fibrillation(AF)in patients with rheumatic diseases(RD)may be due to inflammation.determine morbidity and mortality associated with AF in hospitalized patients with RD.METHODS The National inpatient sample database from October 2015 to December 2017 was analyzed to identify hospitalized patients with RD with and without AF.A subgroup analysis was performed comparing outcomes of AF among different RD.RESULTS The prevalence of AF was 23.9%among all patients with RD(n=3949203).Among the RD subgroup,the prevalence of AF was highest in polymyalgia rheumatica(33.2%),gout(30.2%),and pseudogout(27.1%).After adjusting for comorbidities,the odds of having AF were increased with gout(1.25),vasculitis(1.19),polymyalgia rheumatica(1.15),dermatopolymyositis(1.14),psoriatic arthropathy(1.12),lupus(1.09),rheumatoid arthritis(1.05)and pseudogout(1.04).In contrast,enteropathic arthropathy(0.44),scleroderma(0.96),ankylosing spondylitis(0.96),and Sjorgen’s syndrome(0.94)had a decreased association of AF.The mortality,length of stay,and hospitalization costs were higher in patients with RD having AF vs without AF.Among the RD subgroup,the highest mortality was found with scleroderma(4.8%),followed by vasculitis(4%)and dermatopolymyositis(3.5%).CONCLUSION A highest association of AF was found with gout followed by vasculitis,and polymyalgia rheumatica when compared to other RD.Mortality was two-fold higher in patients with RD with AF.

关 键 词：Atrial fibrillation Rheumatic diseases LUPUS GOUT SCLERODERMA VASCULITIS 

分 类 号：R593.2[医药卫生—内科学] R541.75[医药卫生—临床医学]