Extremely rare case of necrotizing gastritis in a patient with autoimmune hepatitis: A case report  

作　　者：Seung Ki Moon Jeong-Ju Yoo Sang Gyune Kim Young Seok Kim 

机构地区：[1]Department of Internal Medicine,Soonchunhyang University Bucheon Hospital,Bucheon 14584,South Korea [2]Department of Gastroenterology and Hepatology,Soonchunhyang University School of Medicine,Bucheon 14584,South Korea

出　　处：《World Journal of Clinical Cases》2021年第14期3472-3477,共6页世界临床病例杂志

基　　金：Supported by The Soonchunhyang University Research Fund,No.20200037.

摘　　要：BACKGROUND Autoimmune hepatitis can cause liver fibrosis,liver cirrhosis,and hepatocellular carcinoma.Its treatment option include the use of steroids and/or immunesuppressive agents such as azathioprine.However,these drugs have some side effects.Thus,close follow-up is needed during treatment.Here,we present an extremely rare case of a patient with an autoimmune hepatitis who died from necrotizing gastritis during immunosuppressive treatment.CASE SUMMARY A 52-year-old female patient was diagnosed with autoimmune hepatitis.We treated this patient with immunosuppressive agents.High-dose steroid treatment was initially started.Then azathioprine treatment was added while steroid was tapering.Five weeks after the start of treatment,she visited the emergency room due to generalized abdominal pain and vomiting.After computed tomography scan,the patient was diagnosed with necrotizing gastritis and the patient progressed to septic shock.Treatment for sepsis was continued in the intensive care unit.However,the patient died at 6 h after admission to the emergency room.CONCLUSION In patients with autoimmune infections undergoing immunosuppressant therapy,rare complications such as necrotizing gastritis may occur,thus requiring clinical attention.

关 键 词：Autoimmune hepatitis AZATHIOPRINE Case report 

分 类 号：R575.1[医药卫生—消化系统] R573.3[医药卫生—内科学]