A case report of iodine-125 seed placement during operation for the treatment of advanced gallbladder carcinoma with septic shock  

作　　者：Zhuo Zhong Fei Gao Zhuo Lv Zhihui Zhong De Long 

机构地区：[1]Department of Oncology,Guangzhou Hospital of Integrated Traditional and West Medicine,Guangzhou 510800,China [2]Department of Minimally Invasive Interventional Radiology,Sun Yat-sen University Cancer Center,Guangzhou 510060,China

出　　处：《Oncology and Translational Medicine》2021年第2期95-98,共4页肿瘤学与转化医学（英文版）

基　　金：Supported by the Guangzhou Huadu District Science and Technology Project(No.20-HDWS-054).

摘　　要：This case report describes a patient with advanced gallbladder cancer who developed septic shock associated with iodine-125(^(125)I)seed implantation.The treatment process is described to provide a clinical reference for similar cases.A 52-year-old woman with recurrence of advanced gallbladder cancer underwent ^(125)I seed implantation and developed postoperative sepsis with septic shock.The blood culture suggested infection with Aeromonas caviae and Enterococcus faecalis.Vancomycin and imipenem were immediately administered according to the drug sensitivity results,along with immunoglobulin therapy and vasoactive drugs.The patient’s condition gradually stabilized after comprehensive treatment.Sepsis with septic shock is a rare but potentially fatal complication of ^(125)I seed implantation.Timely administration of broad-spectrum antibiotics,immunoglobulin therapy,and vasoactive drugs is very important to stabilize the patient’s condition.Our treatment of this patient can serve as a reference for clinicians to manage this complication in similar cases.

关 键 词：advanced gallbladder cancer ^(125)I seed placement SEPSIS septic shock 

分 类 号：R735.8[医药卫生—肿瘤] R459.7[医药卫生—临床医学]