神经鞘瘤病发病机制综述  

A review of the pathogenesis of schwannomatosis

作　　者：张锦祥 黄永胜 黎凯 郭伟韬 Zhang Jinxiang;Huang Yongsheng;Li Kai;Guo Weitao(The Second Affiliated Hospital of Guangdong Medical University,Zhanjiang 524000,China)

机构地区：[1]广东医科大学附属第二医院,湛江524000

出　　处：《国际医药卫生导报》2021年第8期1108-1113,共6页International Medicine and Health Guidance News

基　　金：2020年度广东医科大学附属第二医院“冲补强”科研培育项目(2020P06)。

摘　　要：神经鞘瘤病(Schwannomatosis,SWNTS),亦称神经纤维瘤3型(neurofibromatosis type 3,NF3),可呈散发性或家族性发病,是一种以多发神经鞘瘤为特征的罕见疾病。因其临床症状与2型神经纤维瘤病(neurofibromatosis type 2,NF2)相似,常常造成两者在鉴别诊断上的困难。NF3的发病机制是极其复杂的,目前尚未有统一定论。本文就近20年来有关NF3的发病机制的研究进展进行综述,以期为进一步开展NF3的发病机制研究提供参考。Schwannomatosis(SWNTS),also known as neurofibromatosis type 3(NF3),is a rare disorder characterized by the predisposition to develop multiple schwannomas and shows sporadic or familial onset.Since the clinical overlap with neurofibromatosis type 2(NF2),it is often difficult to distinguish between schwannomatosis and NF2.The pathogenesis of NF3 is extremely complex,and there is no unified conclusion at present.In this paper,the research progress on the pathogenesis of NF3 in the last 20 years was reviewed,in order to provide references for further research on the pathogenesis of NF3.

关 键 词：神经鞘瘤病 神经纤维瘤病3型 发病机制 

分 类 号：R739.4[医药卫生—肿瘤]