菊粉复合咀嚼片的制备及通便活性研究  

Study on the Preparation of Inulin Compounded Chewable Tablets and Their Laxative Effect

作　　者：王亚坤 陈喜财 陈泽丰 卞旺青 陈霓平 张紫菱 张焜 何燕 WANG Ya-kun;CHEN Xi-cai;CHEN Ze-feng;BIAN Wang-qing;CHEN Ni-ping;ZHANG Zi-ling;ZHANG Kun;HE Yan(School of Biomedical and Pharmaceutical Sciences,Guangdong University of Technology,Guangzhou 510006,Guangdong,China)

机构地区：[1]广东工业大学生物医药学院,广东广州510006

出　　处：《食品研究与开发》2021年第10期82-86,共5页Food Research and Development

基　　金：广东省重点领域研发计划项目(2020B1111120003)。

摘　　要：便秘作为一种常见的胃肠道问题,严重影响了人民的健康。该研究以富含低聚果糖的菊粉、魔芋粉和香蕉粉为主要功效成分,采用湿法制粒压片工艺,筛选研制成菊粉复合咀嚼片,并考察其通便活性。结果表明,最佳原辅料组成为50%菊粉、10%魔芋粉、5%香蕉粉、10%维生素C钠、19%乳糖、2.5%微粉硅胶(内加1%)、1.5%阿司帕坦、含10%聚维酮K30的95%乙醇溶液,30倍活性配方用量对便秘模型具有良好的通便效果,最终获得有一定功效、口感怡人、服用方便、制备简单的菊粉复合咀嚼片。Constipation is a common gastrointestinal problem that poses a serious problem for people′s health.In this study,the authors used a wet granulation tableting method to inulin compound chewable tablets from functional ingredients(i.e.,fructooligosaccharide-enriched inulin,konjac powder,and banana powder)and then investigated the laxative effect of those tablets.Testing revealed that the optimal formulation contained 50%inulin,10%konjac powder,5%banana powder,10%sodium vitamin C,19%lactose,2.5%micropowder silica gel(plus 1%),1.5%aspartame,and 95%ethanol solution containing 10%povidone K30.Results of the laxative experiment indicated that a 30-fold formulation had significant laxative effects in mice.The benefits of chewable tablets included pleasant taste,convenience,ease of preparation,and good laxative effect.

关 键 词：菊粉 咀嚼片 便秘 通便 

分 类 号：TS201.4[轻工技术与工程—食品科学]