Pd-Catalyzed Ortho-Directed C-H Glycosylation of Arenes Using N-linked Bidentate Auxiliaries  

作　　者：Quanquan Wang Wanjun Zhu Qikai Sun Gang He Gong Chen 

机构地区：[1]State Key Laboratory and Institute of Elemento-Organic Chemistry,College of Chemistry,Nankai University,Tianjin 300071,China

出　　处：《Chinese Journal of Chemistry》2021年第3期571-576,共6页中国化学（英文版）

基　　金：G.C.thanks NSFC-91753124,NSFC-21672105,NSFC-21421062,and NSFC-21725204 for financial support of this work.

摘　　要：Main observation and conclusion A set of Pd-catalyzed ortho-directed C-H glycosylation reactions with glycosyl chloride donors using various N-linked bidentate auxil-iaries has been developed for synthesis of C-aryglycosides.A broad range of pyranose and furanose moieties can be installed on the ortho position of arylamine,carbazole,indole and benzylamine type substrates in high yield and with high regio-and diastereoselec-tivity.These auxiliaries can be readily installed and removed under relatively mild conditions.

关 键 词：PD-CATALYZED C-H Bidentate auxiliaries Glycosyl chloride GLYCOSYLATION 

分 类 号：O62[理学—有机化学]