sponsored by the National Key R&D Program of China(Grant No.2023YFA1508800);National Science Foundation(Grant No.22301178);Shanghai Pilot Program for Basic Research-Shanghai Jiao Tong University(Grant No.21TQ1400210);Fundamental Research Funds for the Central Universities(Grant No.22X010201631);the Open Grant from the Pingyuan Laboratory(2023PY-OP-0102);Excellent Young Scientists Fund Program(Overseas),Natural Science Founda-tion of Shanghai(Grant No.21ZR1435600);Shanghai Sailing Program(Grant No 21YF1420600);start-up fundings from Shanghai Jiao Tong University(SJTU);Part of this study was supported by the National Science Foundation(Grant No.82204192 to Y.N.);National Key R&D Program of China(Grant No.2023YFC2308200 to Y.N.);Natural Science Foundation of Jiangsu Province(BK20220471 to Y.N.);Beatriu de Pinós programme from AGAUR(Grant No.2022 BP 00055 to Y.L);the China Postdoctoral Science Foundation(2022M722071 to B.Y.).
Nonclassical C-glycosides,distinguished by their unique glycosidic bond connection mode,represent a promising avenue for the development of carbohydrate-based drugs.However,the accessibility of nonclassical C-glycosid...
the National Natural Science Foundation of China(Nos.22177089,21721005,92153303,22037004,22177088);the Fundamental Research Funds for the Central Universities(2042021kf0211);Translational Medicine and Interdisciplinary Research Joint Fund of Zhongnan Hospital of Wuhan University(Grant No.ZNJC202309).
Comprehensive Summary Pd-mediated bioorthogonal cleavage reactions have been extensively utilized in the activation of prodrug molecules,precise regulation of protein function,and cellular engineering.However,the avai...
funding from the National Natural Science Foundation of China(Nos.22071111 and 22371125);Jiangsu Specially Appointed Professor Plan,and Postgraduate Research&Practice Innovation Program of Jiangsu Province of China(No.KYCX23_1683).
The stereochemical synthesis of highly substituted Danishefsky-type dienes remains unsolved in organic chemistry.We describe a simple and efficient approach for the stereoselective synthesis of Danishefsky-type trisub...
supported by the National Key R&D Program of China (2023YFF0723900);the National Natural Science Foundation of China (22371293, 22171277, 22101291, 21821002);the Program of Shanghai Academic/Technology Research Leader(23XD1424500);the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB0610000);Shanghai Institute of Organic Chemistry (SIOC);State Key Laboratory of Organometallic Chemistry for financial support。
The development of efficient Si–O bond formation reaction with 100% atom-economy, excellent functional group tolerance, and broad scope under mild conditions is highly desired due to the prevalence of silanol, silyl ...
support from the National Natural Science Foundation of China(22271024,21632005)and Changzhou University.
Comprehensive Summary A Pd-catalyzed regioselective hydroesterification of alkyl terminal olefins with aryl formates is described.A wide variety of linear carboxylic esters bearing various functional groups can be obt...
supported financially by National Nature Science Foundation of China(No.22171258);the Youth Innovation Promotion Association CAS(No.2022375);the Biological Resources Programme,Chinese Academy of Sciences(No.KFJ-BRP-008);the Sichuan Science and Technology Program(No.2022ZYD0038)。
Ynones are important skeletons in bioactive molecules and valuable building blocks for organic synthesis,thus great efforts have been devoted to their preparation.While,introducing prochiral substrates to construct yn...
support from the National Natural Science Foundation of China(22101296);the State Key Laboratory of Systems Medicine for Cancer(SB23-09,KF2130-93).
As the chemical industry grapples with the need for more eco-friendly practices,the use of water as a reaction medium is gaining attraction in organic transformations.This mini-review delves into Pd-catalyzed reaction...
supported by the National Natural Science Foundation of China (22171079);the Natural Science Foundation of Shanghai (21ZR1480400);the Shanghai Rising-Star Program (20QA1402300);the Shanghai Municipal Science and Technology Major Project (2018SHZDZX03);the Program of Introducing Talents of Discipline to Universities (B16017);the Fundamental Research Funds for the Central Universities。
The highly diastereoselective dicarbofunctionalization of substituted olefins still remains a daunting challenge in synthetic chemistry.Herein,we report a Pd-catalyzed diastereoselective 1,1-diarylation of 1,1-diaryle...
We are grateful for financial support from National Key Research and Development Program of China(2021YFA0804900);the NSFC(22171082,21971062);the Leading Innovative and Entrepreneur Team Introduction Program of Zhejiang(No.2022R01007);Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism.
We developed a novel Pd-catalyzed[4+4]cycloaddition of(benzo)furan-derived azadienes with homo-TMM all-carbon 1,4-dipoles in situ generated fromα-allyl malonate derivatives,affording an array of benzofuro[3,2-b]azoci...
supported by the Natural Science Foundation of China(Nos.21871293 and 22071264);。
A palladium-catalyzed cascade cyclization of allenylethylene carbonates with 1,3-indandiones was developed, providing biologically interesting tetracyclic dihydrocyclopentaindenofuranone derivatives having three conti...