急性感觉共济失调神经病一例  

Acute sensory ataxia neuropathy: a case report

作　　者：汪伟[1] 孟令超 张伟赫[1] 汪仁斌[1] 袁云[2] Wang Wei;Meng Lingchao;Zhang Weihe;Wang Renbin;Yuan Yun(Department of Neurology,China-Japan Friendship Hospital,Beijing 100029,China)

机构地区：[1]中日友好医院神经内科,北京100029 [2]北京大学第一医院神经内科,北京100034

出　　处：《中华神经科杂志》2021年第5期483-486,共4页Chinese Journal of Neurology

基　　金：国家自然科学基金(81701131)。

摘　　要：报道1例急性感觉共济失调神经病患者的临床、电生理、神经病理特点及其预后。患者为32岁女性,临床表现为感觉异常、感觉性共济失调伴假性手足徐动及腱反射减低,脑脊液呈蛋白-细胞分离,肌电图及腓肠神经活组织检查符合急性重度活动性感觉轴索性周围神经病特点,经静脉注射丙种球蛋白联合大剂量激素冲击治疗,患者四肢烧灼刺痛感逐渐缓解。随访1年余,患者持物不稳症状缓慢改善,多次随访肌电图检查提示双下肢H反射波幅随临床症状改善而缓慢恢复。The clinical,neuroelectrophysiological,neuropathological characteristics and outcome of a case of acute sensory axonopathy are reported.The patient was a 32-year-old female.She presented with acute onset sensory abnormalities,sensory ataxia,pseudoathetosis and areflex.Lab testing showed cerebrospinal fluid albumin cytologic dissociation.Electromyography studies and sural nerve pathology were consistent with acute sensory axonopathy.Treatment including intravenous immunoglobulin and steroid therapy was provided.Her symptoms recovered slowly without relapse,so did tibial H-reflex amplitudes.

关 键 词：共济失调 H反射 感觉轴索神经病 假性手足徐动 

分 类 号：R745.43[医药卫生—神经病学与精神病学]