Efficacy of combination of localized closure,ethacridine lactate dressing,and phototherapy in treatment of severe extravasation injuries:A case series  

作　　者：Yan-Xu Lu Ying Wu Peng-Fei Liang Rong-Chan Wu Ling-Yun Tian Hui-Ying Mo 

机构地区：[1]Xiangya Stomatological Hospital&School of Stomatology,Central South University,Changsha 410000,Hunan Province,China [2]Teaching and Research Section of Clinical Nursing,Department of Burn and Reconstructive Surgery,Xiangya Hospital of Central South University,Changsha 410008,Hunan Province,China [3]Department of Burn and Reconstructive Surgery,Xiangya Hospital of Central South University,Changsha 410008,Hunan Province,China [4]Phase 1 Clinical Trial Center,Xiangya Hospital of Central South University,Changsha 410008,Hunan Province,China [5]School of Nursing,Anhui University of Chinese Medicine,Hefei 230012,Anhui Province,China

出　　处：《World Journal of Clinical Cases》2021年第18期4599-4606,共8页世界临床病例杂志

基　　金：Supported by Natural Science Foundation of Hunan Provincial Science and Technology Department,No.2019JJ40527.

摘　　要：BACKGROUND The management of severe extravasation injuries is still controversial.Extravasation injuries can be treated in many ways.AIM To present a series of patients with severe extravasation injuries due to infusion who were managed with ethacridine lactate dressing combined with localized closure and phototherapy.METHODS In this study,we evaluated the data of eight patients,including six from the Department of Burn,one(with colorectal carcinoma)from the Veteran Cadre Department,and one(with leukemia)from the Hematology Department.Of these,three patients were male and five were female.Age of the patients ranged from 10 mo to 72 years,including two children(10 and 19 mo of age).In this study,the infusion was stopped immediately when the extravasation was identified.The extravasation event was managed routinely using a blocking solution.A ring-shaped localized closure was performed using the blocking agents.Moreover,ethacridine lactate dressing and phototherapy were applied for 3-5 d.RESULTS In this study,the drugs contained in the infusates were iodixanol,norepinephrine,alprostadil,amino acids,fat emulsion,cefoselis,cefoxitin,and potassium chloride+concentrated sodium chloride.All of the patients achieved complete healing after treatment and no obvious adverse reactions were observed.CONCLUSION The treatment of severe extravasation injuries using a combination of localized closure,ethacridine lactate dressing,and phototherapy resulted in satisfactory outcomes in patients.

关 键 词：EXTRAVASATION CLOSURE Ethacridine lactate DRESSING PHOTOTHERAPY TREATMENT 

分 类 号：R969.4[医药卫生—药理学]