supported by the National Natural Science Foundation of China (22234003,22325401,22074036,22404128);the Program of Excellent Doctor of Zhongnan Hospital of Wuhan University (ZNYB2022009);the Zhongnan Hospital of Wuhan University Science,Technology and Innovation Seed Fund (CXPY2023027);the Guangdong Basic and Applied Basic Research Foundation (2023A1515110867);the National Research Foundation of Korea for the grant funded by the Korean government (MSIT) (2022R1A2C3005420)。
Phototherapy has emerged as a promising modality in modern medicine,attracting significant attention due to its non-invasiveness,exceptional spatiotemporal controllability,and reduced side effects.Advanced technologie...
funded by Young Elite Scientists Sponsorship Program by CACM(No.2021-QNRC2-A03);the Beijing Natural Science Foundation(No.7202121);the National Natural Science Foundation of China(No.81703715).
Phototherapy, including photodynamic therapy(PDT) and photothermal therapy (PTT), is a promisingmethod of tumor treatment, which has the advantages ofstrong specificity and small side effects. However, PDT willaggrava...
supported by the National Natural Science Foundation of China(No.62071413);the Hebei Natural Science Foundation of China(Nos.C2019203556 and F2020203056);the Natural Science Foundation of Hebei Province for Innovation Group Project,China(No.C2022203003)。
Photodynamic therapy(PDT)has significant advantages in treating primary tumors.However,the hypoxic tumor microenvironment hinders the generation of sufficient reactive oxygen species during PDT to effectively kill tum...
Taishan Scholars Program of Shandong Province(tsqn202103189);National Natural Science Foundation of China(81771298).
Peripheral nerve injury(PNI)usually causes severe motor,sensory and autonomic dysfunction.In addition to direct surgical repair,rehabilitation exercises,and traditional physical stimuli,for example,electrical stimulat...
supported by the National Natural Science Foundation of China(NSFC)projects(Nos.22122705,22077139);National Key R&D Program of China(No.2022YFE0199700);CAMS Innovation Fund for Medical Sciences(CIFMS)(No.2021-I2M-1-054);the Disciplines Construction Project(No.201920200805)。
Antibiotic resistance poses a critical threat to human healthcare,largely driven by bacterial biofilms.These biofilms resist the immune system and antibiotics,rendering enclosed microbial cells 10-1000times more antib...
financially supported by the Natural Science Foundation of China(No.22077021);the Natural Science Foundation of Guangxi(No.2022GXNSFGA035003)。
Cisplatin resistance is the main cause for the failure of cancer therapy.To solve the problem,we proposed to develop a novel human serum albumin(HSA)nanoplatform to integrate chemotherapy,photothermal therapy(PTT)and ...
supported by the National Natural Science Foundation of China(Nos.22175107,22305140,51603184,82270531);Zhejiang Provincial Natural Science Foundation of China(Nos.LY21E030002,LY22H020003);Scientific Research Foundation of Zhejiang University City College(No.J-202104);Hangzhou Science and Technology Bureau of China(No.202203B27)。
Photodynamic therapy(PDT)has garnered significant attention as a promising approach to cancer therapy,harnessing the combined benefits of localized light treatment and the accompanying host immune response.In this stu...
This work was supported by the National Natural Science Foundation of China(22374092,and 22104074);Natural Science Foundation of Shandong Province(ZR2022YQ10);Natural Science Foundation of Shandong Province(Major Basic Research Project)(ZR2023ZD44);Project of Shandong Provincial Laboratory(SYS202207);Youth Innovation Science and Technology Program of Higher Education Institution of Shandong Province(2022KJ338).
Malignant glioma remains one of the most aggressive intracranial tumors with devastating clinical outcomes despite the great advances in conventional treatment approaches,including surgery and chemotherapy.Spatio-temp...
Basic and Applied Basic Research Foundation of Guangdong Province,Grant/Award Numbers:2021A1515110373,2023A1515011924;Science and Technology Planning Project of Guangzhou-Basic and Applied Basic Research Project,Grant/Award Number:202201011505;Major Scientific and Technological Special Project in the Precision Medical Field of Guangdong Province,Grant/Award Number:2019B020232003;National Key Research and Development Program of China,Grant/Award Numbers:2021YFA1300604,2021YFE0202400;National Natural Science Foundation of China,Grant/Award Numbers:22205096,31971293;Outstanding Youths Development Scheme of Nanfang Hospital,Southern Medical University,Grant/Award Number:2021J002;National Science Fund for Distinguished Young Scholars,Grant/Award Number:82025024。
Antimicrobial resistance(AMR)remains an urgent and formidable challenge to global public health.Developing new medicines or alternative therapies to address AMR is imperative.Herein,we rationally designed and synthesi...
National Natural Science Foundation of China,Grant/Award Numbers:22077038,52325304,21877042;Huazhong University Supportive Fund for Fundamental Research。
The energy dissipation pathways of a photosensitizer for phototherapies,including photodynamic therapy(PDT)and photothermal therapy(PTT),compete directly with that of itsfluorescence(FL)emission.Enriching heavy atoms o...