认知障碍对老年人跌倒风险的影响及其神经生物学机制  

The effect of cognitive impairment on fall risk in the elderly and the underlying neurobiological mechanisms

作　　者：周容 黄灵燕[1] 吕娇娇[1] Zhou Rong;Huang Lingyan;Lyu Jiaojiao(Key Laboratory of Exercise and Health Sciences of Ministry of Education,Shanghai University of Sport,Shanghai 200438,China)

机构地区：[1]上海体育学院运动健身科技省部共建教育部重点实验室,200438

出　　处：《中华老年医学杂志》2021年第6期793-797,共5页Chinese Journal of Geriatrics

基　　金：教育部人文社会科学研究一般项目(19YJCZH115);国家自然基金重点项目(11932013)。

摘　　要：认知障碍会增加跌倒风险,是跌倒的重要危险因素。同时,早期的步态障碍(跌倒的主要危险因素)也可以预测神经退行性疾病。因此,认知障碍和跌倒并不是两个独立的问题,二者高度相关并可能存在共同的病理机制。本文将结合国内外相关研究成果,探讨认知障碍对老年人跌倒风险的影响及其神经生物学机制,并为未来跌倒预防与相关临床干预提供理论指导和参考建议。Cognitive impairment increases the risk of falls and is an important risk factor for falls.At the same time,early gait disorders(a major risk factor for falls)can also predict the development of neurodegenerative diseases.Therefore,cognitive impairment and falls are not separate problems,but are highly correlated and may share common pathological mechanisms.This article explores the impact of cognitive impairment on fall risk in the elderly and its neurobiological mechanisms based on relevant nationally and international research,and provides a theoretical framework and recommendations for fall prevention and clinical intervention in the future.

关 键 词：认知障碍 神经生物学 跌倒 

分 类 号：R749.1[医药卫生—神经病学与精神病学]