A vestigial pathway for sex differences in immune regulation  

作　　者：Yun Liang J Michelle Kahlenberg Johann E Gudjonsson 

机构地区：[1]Department of Dermatology,University of Michigan,Ann Arbor,MI 48109,USA [2]Division of Rheumatology,Department of Internal Medicine,University of Michigan,Ann Arbor,MI 48109,USA

出　　处：《Cellular & Molecular Immunology》2017年第7期578-580,共3页中国免疫学杂志（英文版）

基　　金：supported by the US National Institutes of Health(K08-AR060802 and R01-AR069071 to JEG,and R03-AR066337 and K08-AR063668 to JMK);an A Alfred Taubman Medical Research Institute Kenneth and Frances Eisenberg Emerging Scholar Award(JEG);the Doris Duke Charitable Foundation(2013106 to JEG);a Pfizer Aspire Award(JEG).

摘　　要：Autoimmune diseases have a strikingly higher prevalence in women compared to men,with approximately 80%of individuals affected with autoimmune diseases being female.The nature of this sex-bias has remained unclear,but sex hormones have previously been implicated as the leading underlying cause.In this research highlight,we discuss a recently identified transcription factor。

关 键 词：DISEASES AUTOIMMUNE PREVALENCE 

分 类 号：R59[医药卫生—内科学]