Polysubstituted Isoflavonoids from Spatholobus suberectus,Flemingia macrophylla,and Cudrania cochinchinensis  

作　　者：Li-Xia Wang Hai-Rong Zheng Fu-Cai Ren Tian-Gc Chen Xiang-Mei Li Xian-Jun Jiang Fei Wang 

机构地区：[1]BioBioPha Co.,Ltd.,Kunming 650201,People’s Republic of China

出　　处：《Natural Products and Bioprospecting》2017年第2期201-206,共6页应用天然产物（英文）

基　　金：supported by the"Large-scale Compound Library"project of National Development and Reform Commission of China.

摘　　要：Four hitherto unknown polysubstituted isofiavonoids,including three isofiavans:7,4'-dihydroxy-8,2',3'-trimethoxyisofiavan(1),7,2',4'-trihydroxy-8,3'-dimethoxyisofiavan(2),and 7,2',4'-trihydroxy-5-methoxyisofiavan(3),and one prenylated isofiavone cudraisofiavone M(4)were isolated from the ethanol extracts of Spatholobus suberectus(for 1 and 2),Flemingia macrophylla(for 3),and Cudrania cochinchinensis(for 4),respectively.Their structures were estab­lished on the basis of extensive spectroscopic analysis.Compounds 1 and 4 exhibited weak cytotoxic activity against five human cancer cell lines(HL-60,A-549,SMMC-7721,MCF-7,and SW-480).

关 键 词：Spatholobus suberect us Flemingia macrophylla Cudrania cochinchinensis Isofiavan Isofiavone CYTOTOXICITY 

分 类 号：R73[医药卫生—肿瘤]