Three new triterpenoids from Rubia schumanniana  

作　　者：Bin KUANG Jing HAN Guang-Zhi ZENG Xiao-Qiang CHEN Wen-Jun HE Ning-Hua TAN 

机构地区：[1]State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming 650201,China [2]Graduate University of Chinese Academy of Sciences,Beijing 100049,China

出　　处：《Natural Products and Bioprospecting》2012年第4期166-169,共4页应用天然产物（英文）

基　　金：supported by the National Natural Science Foundation of China(U1032602,91013002,30725048);the National New Drug Innovation Major Project of China(2011ZX09307-002-02);the National Basic Reaearch Program of China(2009 CB522300).

摘　　要：Three new triterpenoids,3β-hydroxy-urs-30-p-Z-hydroxycinnamoyl-12-en-28-oic-acid(1),3β-hydroxy-olean-30-p-E-hydroxycinnamoyl-12-en-28-oic-acid(2)and 3β,6α-dihydroxy-urs-14-en-12-one(3),together with seven known triterpenoids,were isolated from the roots of Rubia schumanniana.Their structures were established by means of spectroscopic analysis.All compounds were evaluated for cytotoxic activity,and compounds 2-6 showed cytotoxicity with the IC50 values of 10.75~18.87μg/mL.

关 键 词：Rubia schumanniana TRITERPENOID CYTOTOXICITY 

分 类 号：O62[理学—有机化学]