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作 者:Giuseppe Grassi Ilaria Lenci Alessandro Signorello Martina Milana Leonardo Baiocchi
机构地区:[1]Hepatology Unit,University of Tor Vergata,Rome 00100,Italy
出 处:《World Journal of Gastrointestinal Endoscopy》2021年第7期210-220,共11页世界胃肠内镜杂志(英文版)(电子版)
摘 要:Patients with liver cirrhosis are fragile and present specific clinical hallmarks.When undergoing to gastrointestinal(GI)endoscopy,these subjects require an individual pre evaluation,taking into account:Level of haemostasis impairment,the individual risk of infection,the impact of sedation on hepatic encephalopathy and other factors.The overall assessment of liver function,employing common scoring systems,should be also assessed in the preprocedural phase.Beside some common general problems,regarding GI endoscopy in cirrhotic subjects,also specific issues are present for some frequent indications or procedures.For instance,despite an increased incidence of adenomas in cirrhosis,colon cancer screening remains suboptimal in subjects with this disease.Several studies in fact demonstrated liver cirrhosis as a negative factor for an adequate colon cleansing before colonoscopy.On the other hand,also the routine assessment of gastroesophageal varices during upper GI endoscopy presents some concern,since important inter-observer variability or incomplete description of endoscopic findings has been reported in some studies.In this review we discussed in details the most relevant issues that may be considered while performing general GI endoscopic practice,in patient with cirrhosis.For most of these issues there are no guidelines or clear indications.Moreover until now,few studies focused on these aspects.We believe that targeting these issues with corrective measures may be helpful to develop a tailored endoscopic approach for cirrhosis,in the future.
关 键 词:Gastrointestinal endoscopy CIRRHOSIS SEDATION Infection Gastroesophageal varices COLONOSCOPY Bowel cleansing Liver transplantation
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