Prenylated Coumarins from Heracleum stenopterum,Peucedanum praeruptorum,Clausena lansium,and Murraya paniculata  

作　　者：Xiang-Mei Li Xian-Jun Jiang Ku Yang Li-Xia Wang Shi-Zhen Wen Fei Wang 

机构地区：[1]BioBioPha Co.,Ltd.,Kunming 650201,People’s Republic of China

出　　处：《Natural Products and Bioprospecting》2016年第5期233-237,共5页应用天然产物（英文）

摘　　要：Four hitherto unknown prenylated coumarins,namely 600-O-b-D-apiofuranosylapterin(1),40-O-isobutyroylpeguangxienin(2),6-(3-methyl-2-oxobutyroyl)-7-methoxycoumarin(3),and 6-hydroxycoumurrayin(4),were isolated from the ethanol extract of Heracleum stenopterum,Peucedanum praeruptorum,Clausena lansium,and Murraya paniculata,respectively.Their chemical structures were established on the basis of extensive spectroscopic analysis.Compound 2 exhibited in vitro cytotoxic activity against five human cancer cell lines(HL-60,A-549,SMMC-7721,MCF-7,and SW-480)with IC50 values ranging from 15.9 to 23.2μM.

关 键 词：Heracleum stenopterum Peucedanum praeruptorum Clausena lansium Murraya paniculata Prenylated coumarin CYTOTOXICITY 

分 类 号：R73[医药卫生—肿瘤]