GBW(E)100674乙腈中展青霉素溶液标准物质的研制  

Development of Certified Reference Materials of Patulin in Acetonitrile GBW(E)100674

作　　者：李先江 国振[1] 赵光亮 李秀琴[1] 张庆合[1] 李红梅[1] LI Xianjiang;GUO Zhen;ZHAO Guangliang;LI Xiuqin;ZHANG Qinghe;LI Hongmei(National Institute of Metrology,Beijing 100029,China)

机构地区：[1]中国计量科学研究院,北京100029

出　　处：《计量科学与技术》2021年第6期34-38,24,共6页Metrology Science and Technology

基　　金：国家重点研发计划(2016YFF0201106)。

摘　　要：本课题研制了乙腈中展青霉素的溶液标准物质1种,并已成功申报为国家二级标准物质(GBW(E)100674)。该溶液标准物质以展青霉素纯度国家二级标准物质(GBW(E)100673)为原料,采用重量容量法配制。依据JJF 1343-2012《标准物质定值的通用原则及统计学原理》的要求,本研究采用液相色谱法对乙腈中展青霉素溶液标准物质进行均匀性、短期稳定性和长期稳定性的评价。定值不确定度包含原料纯度、溶液配制、均匀性、短期稳定性和长期稳定性五个方面引入的不确定度。最终,该溶液标准物质GBW(E)100674的定值结果为100µg/mL,不确定度为2%。本研究研制展青霉素溶液标准物质的量值具有溯源性和准确性,可以支持国家食品安全检测的需要。A solution Certified Reference Material(CRM)of patulin was developed and has been officially approved with the code of GBW(E)100674.This CRM was prepared by using the gravimetric-volumetric method with solid materials of the patulin purity CRM GBW(E)100673.According to the general and statistical principles for characterization of reference materials in JJF 1343-2012,homogeneity and stability tests were carried out with liquid chromatography.Uncertainty was evaluated in consideration of solid purity,solution preparation,homogeneity,short-term stability,and longterm stability.The certified value of the patulin solution is 100µg/mL with an expanded uncertainty of 2%(k=2).The atulin solution CRM with a traceable and accurate value can support food safety tests in China.

关 键 词：展青霉素 标准物质 均匀性 稳定性 不确定度 乙腈 

分 类 号：TS207.5[轻工技术与工程—食品科学]