Lactobacillus casei protects intestinal mucosa from damage in chicks caused by Salmonella pullorum via regulating immunity and the Wnt signaling pathway  

作　　者：Deng Ziteng Han Deping Wang Yuying Wang Qiuzhen Ma Yunfei 

机构地区：[1]School of Veterinary Medicine,China Agricultural University,Beijing 100193,China

出　　处：《解剖学杂志》2021年第S01期159-159,共1页Chinese Journal of Anatomy

摘　　要：This study is to explore the mechanisms underlying the protective effects of Lactobacillus casei(L.casei)on the intestinal mucosal barrier of chicks infected with Salmonella pullorum(S.pullorum)through histological,immunological,and molecular biology methods.The results showed that L.casei significantly reduced the diarrhea rate,increased the daily weight gain,and maintained normal levels of IgA,IgM,and IgG in the serum of chicks infected with S.pullorum.Furthermore,we found that L.casei markedly improved the immunity of gut mucosa by regulating cytokine and chemokine receptor balance,elevating the number of intraepithelial lymphocytes.

关 键 词：IMMUNITY MUCOSA protective 

分 类 号：R57[医药卫生—消化系统]