安徽省淮南市2015-2019年围产儿出生缺陷监测情况分析  

Monitoring of birth defects in perinatal infants born during 2015-2019 in Huainan City,Anhui Province

作　　者：苏珍 田慧子 王允荟 Su Zhen;Tian Huizi;Wang Yunhui(Department of Health,Huainan Maternal and Child Health Hospital,Huainan 232007,Anhui Province,China)

机构地区：[1]淮南市妇幼保健院保健部,安徽省232007

出　　处：《中国基层医药》2021年第8期1187-1191,共5页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的:分析安徽省淮南市围产儿出生缺陷监测情况。方法:选取2015-2019年淮南市9家国家级和省级出生缺陷监测医院的围产儿资料,分析5年来出生缺陷的变化情况,城乡、性别分布情况,≥28周出生缺陷发生率,缺陷种类以及出生缺陷发生的相关因素。结果:2015-2019年共监测围产儿90 466例,出生缺陷发生率为89.87/万,安徽省出生缺陷发生率为139.74/万;<28周平均占全孕周出生缺陷的比例为30.93%,2015-2019年呈现逐年升高趋势,构成比分别为14.84%、31.69%、34.83%、32.84%、34.02%。2015-2019年出生缺陷顺位:前5位分别为多指(趾)189例(20.89/万),总唇裂96例(10.61/万),外耳畸形79例(8.73/万),先天性心脏病65例(7.19/万),并指(趾)40例(4.42/万)。男性出生缺陷发生率为102.77/万,女性为85.28/万。城镇出生缺陷发生率为107.38/万,农村为79.60/万。结论:淮南市≥28周出生缺陷发生率低于全省水平,不同年份存在差异;男性高于女性;从2016年起城镇高于乡村;出生缺陷种类以多指(趾)、外耳畸形、先天性心脏病、总唇裂、并指(趾)为主,<28周缺陷儿检出率逐年增加,及早发现<28周缺陷儿,早期干预可有效降低新生儿缺陷的发生率,提高淮南市出生的人口素质。Objective To analyze birth defects in perinatal infants in Huainan city,Anhui province.Methods The data of perinatal infants with birth defects born during 2015-2019 who were monitored in nine national and provincial birth defect monitoring hospitals in Huainan City were collected.The changes in birth defects,the incidence of birth defects in infants≥28 weeks,urban and rural area distribution of birth defects,type of defects,and the related factors of birth defects during a 5-year study period were analyzed.Results A total of 90466 perinatal infants with the incidence of birth defects of 89.87/10000 were monitored during 2015-2019.The incidence of birth defects in Anhui Province was 139.74/10000.The proportion of preterm infants<28 weeks with birth defects among full-term births with birth defects was 30.93%and the proportion increased year by year during 2015-2019,with the proportion of 14.84%,31.69%,34.83%,32.84%and 34.02%respectively.The top five birth defects detected during 2015-2019 were multiple fingers(toes)(n=189,20.89/10000),cleft lip(n=96,10.61/10000),external ear deformity(n=79,8.73/10000),congenital heart disease(n=65,7.19/10000)and syndactyly(n=40,4.42/10000).The incidence of birth defects in males and females was 102.77/10000 and 85.28/10000,respectively.The incidence of birth defects in urban and rural areas were 107.38/10000 and 79.60/10000,respectively.Conclusion The incidence of birth defects in preterm infants<28 weeks in Huainan City was lower than that in the whole Anhui Province.The incidence of birth defects in Huainan City differed in different years.The incidence of birth defects in males was higher than that in females.From 2016,the incidence of birth defects in urban area was higher than that in rural area.Birth defects mainly consisted of multiple fingers(toes),external ear deformity,congenital heart disease,cleft lip and syndactyly.The detection rate of birth defects in preterm(<28 weeks)patients was increased year by year.Early intervention effectively decreased the incidence of b

关 键 词：围生医学 胎儿监测 出生缺陷 多指(趾)畸形 唇裂 耳畸形 获得性 心脏缺损 先天性 并指(趾) 

分 类 号：R174[医药卫生—妇幼卫生保健]