Modulation of the intracellular inhibitory checkpoint SHP-1 enhances the antitumor activity of engineered NK cells  

作　　者：Aviad Ben-Shmuel Guy Biber Batel Sabag Mira Barda-Saad 

机构地区：[1]The Mina and Everard Goodman Faculty of Life Sciences,Bar-Ilan University,Ramat-Gan,5290002,Israel

出　　处：《Cellular & Molecular Immunology》2021年第5期1314-1316,共3页中国免疫学杂志（英文版）

基　　金：funded by Israel Science Foundation grant no.747/13;grant no.3-10151 from the Chief Scientist Office of the Ministry of Health;a Taubenblatt Family Foundation Bio-Medicine excellence grant.

摘　　要：Natural killer(NK)cells are innate lymphoid cells(ILCs)that eliminate virally infected and cancerous cells.NK cells directly induce target cell death and release cytokines and chemokines that activate the adaptive arm of the immune system.

关 键 词：KILLER death LYMPHOID 

分 类 号：R392[医药卫生—免疫学]