非黑素瘤皮肤癌患者生活质量及影响因素调查  

A survey on quality of life and its influencing factors among patients with non-melanoma skin cancers

作　　者：刘倩 李国宏[2] 陈炳为[3] Liu Qian;Li Guohong;Chen Bingwei(Department of Plastic Surgery,Hospital of Dermatology,Chinese Academy of Medical Sciences and Peking Union Medical College,Nanjing 210042,China;Nursing Department,Zhongda Hospital,Southeast University,Nanjing 210009,China;Department of Epidemiology and Biostatistics,School of Public Health,Southeast University,Nanjing 210009,China)

机构地区：[1]中国医学科学院、北京协和医学院皮肤病医院整形外科,南京210042 [2]东南大学附属中大医院护理部,南京210009 [3]东南大学公共卫生学院流行病与卫生统计学系,南京210009

出　　处：《中华皮肤科杂志》2021年第9期819-821,共3页Chinese Journal of Dermatology

摘　　要：目的调查非黑素瘤皮肤癌(NMSC)患者生活质量及其影响因素。方法2017年6月至2020年1月,通过自制问卷及皮肤病生活质量指数量表(DLQI)调查153例在中国医学科学院皮肤病医院整形外科住院接受手术治疗的NMSC患者的人口学、临床、行为学资料,并计算DLQI评分评估其生活质量。采用χ^(2)检验、Kruskal-Wallis H检验、多因素Logistic回归分析NMSC患者生活质量的影响因素。结果回收有效问卷146份(95.4%)。146例患者年龄31~92岁,101例(69.2%)60岁以上,59例(40.4%)有长期紫外线暴露史。基底细胞癌(BCC)66例(45.2%),侵袭性鳞状细胞癌(SCC)57例(39.0%),乳房外Paget病16例(11.0%)及Bowen病7例(4.8%)。DLQI评分中位数[M(P25,P75)]为3(1,7),99例(67.8%)生活质量受到影响,52例(35.6%)受到轻度影响,47例(32.2%)受到中度以上影响。多因素Logistic回归分析显示,皮肤癌类型、长期紫外线照射史、3个及以上子女数量影响患者的生活质量。结论NMSC降低患者的生活质量,且皮肤癌类型、长期紫外线照射史、子女数量是NMSC患者生活质量的影响因素。Objective To investigate quality of life and its influencing factors among patients with non-melanoma skin cancers(NMSC).Methods From June 2017 to January 2020,demographic,clinical and behavioral data were collected from 153 inpatients with NMSC,who received surgeries in Department of Plastic Surgery,Hospital of Dermatology,Chinese Academy of Medical Sciences and Peking Union Medical College,by using a self-made questionnaire and the dermatology life quality index(DLQI)scale,and DLQI score was calculated to evaluate the quality of life of the patients.Chi-square test,Kruskal-Wallis H test,and multivariate logistic regression model were used to analyze factors influencing the quality of life of NMSC patients.Results A total of 146(95.4%)valid questionnaires were collected.The 146 patients were 31-92 years old,and 101(69.2%)of them were over 60 years old,and 59(40.4%)had a history of long-term ultraviolet exposure.There were 66 cases(45.2%)of basal cell carcinoma(BCC),57(39.0%)of invasive squamous cell carcinoma(SCC),16(11.0%)of extramammary Paget disease and 7(4.8%)of Bowen disease.The median DLQI score(M[P25,P75])was 3(1,7).The quality of life were affected in 99(67.8%)patients,including 52(35.6%)mildly affected,and 47(32.2%)moderately to extremely severely affected.Multivariate logistic regression analysis showed that the skin cancer type,long-term ultraviolet exposure history,and having 3 or more children affected the quality of life of the patients with NMSC.Conclusion NMSC decrease the quality of life of the patients,and the type of skin cancers,history of long-term ultraviolet exposure and number of children are the factors influencing the quality of life of patients with NMSC.

关 键 词：皮肤肿瘤 生活质量 疾病影响状态调查 问卷调查 

分 类 号：R739.5[医药卫生—肿瘤]