Hepatic cecum:a key integrator of immunity in amphioxus  

作　　者：Baozhen Qu Shicui Zhang Zengyu Ma Zhan Gao 

机构地区：[1]Department of Marine Biology,Institute of Evolution and Marine Biodiversity,Ocean University of China,Qingdao,266003,China [2]Laboratory for Marine Biology and Biotechnology,Pilot National Laboratory for Marine Science and Technology(Qingdao),Qingdao,266237,China

出　　处：《Marine Life Science & Technology》2021年第3期279-292,共14页海洋生命科学与技术（英文）

基　　金：This work was supported by the grants of National Natural Science Foundation of China(32070514;31601862).

摘　　要：The vertebrate liver is regarded as an organ essential to the regulation of immunity and inflammation as well as being central to the metabolism of nutrients.Here,we discuss the functions that the hepatic cecum of amphioxus plays in the regulation of immunity and inflammation,and the molecular basis of this.It is apparent that the hepatic cecum performs important roles in the immunity of amphioxus including immune surveillance,clearance of pathogens and acute phase response.Therefore,the hepatic cecum,like the vertebrate liver,is an organ functioning as a key integrator of immunity in amphioxus.

关 键 词：Acute phase response AMPHIOXUS Hepatic cecum IMMUNITY INFLAMMATION 

分 类 号：Q95[生物学—动物学]