质谱技术在甲状腺乳头状癌研究中的应用进展  

Proteomics research progress of thyroid cancer

作　　者：宋丽娜[1] 令狐志宏[1] 王晶莹[1] 李晓燕[2] Song Lina;Linghu Zhihong;Wang Jingying;Li Xiaoyan(Department of Laboratory,China-Japan Union Hospital of Jilin University,Changchun 130033,China;Department of Nosocomial Infection Management,Stomatological Hospital of Jilin University,Changchun 130000,China)

机构地区：[1]吉林大学中日联谊医院检验科,长春130033 [2]吉林大学口腔医院,医院感染管理部,长春130000

出　　处：《中华实验外科杂志》2021年第9期1857-1859,共3页Chinese Journal of Experimental Surgery

摘　　要：甲状腺癌是对内分泌系统影响最大的恶性肿瘤,其中甲状腺乳头状癌是最常见的类型,多年来发病率不断上升。质谱技术有助于寻找肿瘤发展中的关键分子及筛选与肿瘤相关的潜在的标志物,近年来已被广泛用于肺癌、食管癌、胃癌、卵巢癌、宫颈癌、甲状腺癌等各种恶性肿瘤的研究中,成为肿瘤潜在标记物检测的强有力的工具。现对近年来质谱技术在甲状腺乳头状癌研究中的应用进展做一综述。Thyroid cancer is the malignant tumor that has the greatest impact on the endocrine system,among which papillary thyroid carcinoma(PTC)is the most common type,and its incidence has been increasing over the years.Proteomics technology helps to find key molecules in tumor development and screen potential tumor-related markers.In recent years,it has been widely used in the research of various malignant tumors such as lung cancer,esophageal cancer,gastric cancer,and thyroid cancer,and become a powerful tool for the detection of potential tumor markers.This article summarizes the application progress of mass spectrometry in the research of papillary thyroid carcinoma in recent years.

关 键 词：甲状腺癌 质谱 进展 

分 类 号：R736.1[医药卫生—肿瘤]