Multiple autoimmune antibody limbic encephalitis:a case in a pregnant woman  

作　　者：Meha Goyal Kasey L.Gildersleeve Stuart L.Tomko Joseph S.Kass 

机构地区：[1]Department of Neurology,Baylor College of Medicine,Houston,TX 77030,USA [2]Department of Neurology,The University of Texas Health Science Center,Houston,TX 77030,USA [3]Department of Neurology,Ben Taub General Hospital,Houston,TX 77030,USA

出　　处：《Neuroimmunology and Neuroinflammation》2015年第1期46-48,共3页神经免疫与神经炎症（英文版）

摘　　要：Autoimmune limbic encephalitis is most commonly associated with antibodies against the N‑methyl‑D‑aspartate receptor(NMDAR),among other neuronal cell surface receptors.Here,a case of a pregnant female with limbic encephalitis in the presence of multiple additional autoimmune antibodies is described.The patient was a 36‑year‑old female who presented with 4 days of confusion,hallucinations,hypersexuality,disinhibition,and pressured speech.The patient’s work‑up detected the presence of anti‑NMDAR antibodies,anti‑glutamic acid decarboxylase antibodies,and a yet uncharacterized neuronal autoantibody.The patient was also found to be pregnant.No evidence of ovarian or other pelvic malignancy was discovered.Symptomatic control was achieved with plasma exchange.

关 键 词：AUTOIMMUNE ENCEPHALITIS glutamic acid decarboxylase LIMBIC N‑methyl‑D‑aspartate 

分 类 号：R74[医药卫生—神经病学与精神病学]