Neurocysticercosis in Nepal:a retrospective clinical analysis  

作　　者：Rajeev Ojha Dinesh Bikram Shah Amina Shrestha Sunil Koirala Apurba Dahal Khem Adhikari Anjal Bisht Pratik Wagle 

机构地区：[1]Department of Medicine,Neurology Unit,National Academy of Medical Sciences,Bir Hospital,Mahaboudha,Kathmandu 44600,Nepal [2]Department of Medicine,Om Hospital and Research Center,Chabahil,Kathmandu 44602,Nepal

出　　处：《Neuroimmunology and Neuroinflammation》2015年第1期167-170,共4页神经免疫与神经炎症（英文版）

摘　　要：Aim:The prevalence of epilepsy is higher in Nepal.This study was conducted to analyze the clinical manifestations of neurocysticercosis(NCC)among seizure patients admitted to our center.Methods:We retrospectively studied all the NCC patients admitted to Neurology Department,Bir Hospital,Kathmandu,Nepal from April 2012 to February 2014.Computer tomography/magnetic resonance imaging(CT/MRI)head,clinical profile,lab investigations and exclusion of other causes were the basis of the NCC diagnosis.Chi-square and Student’s t-test were used for comparison of variables.Results:Out of 131 seizure patients admitted,21 patients were diagnosed with NCC[mean age:33.95±16.41;male:15(71.4%),female:6(28.6%)].Generalized tonic clonic seizure was the most common seizure type in NCC patients(18 patients;85.7%),two of them had status epilepticus during presentation in Emergency Department.Three patients had focal seizure,one with epilepsia partialis continua.Neuroimaging showed multiple NCC lesions in 8(38.1%)and a single NCC lesion in 13(61.9%)patients.Seven of them(33.3%)sought traditional healers before being presented to our center.Eight patients(38.1%)were treated with antiepileptics in local health-post without neuroimaging studies done.Calcified stage of NCC was the most frequent CT/MRI findings(12 patients;57.1%).Phenytoin was preferred both by physicians and patients due to its low cost.Conclusion:NCC is a common finding among seizure patients in Nepal.Poor economic status,illiteracy and underdeveloped rural society are the major challenges in prevention and treatment of NCC.

关 键 词：CYSTICERCOSIS EPILEPSY NEUROCYSTICERCOSIS Nepal south Asia 

分 类 号：R73[医药卫生—肿瘤]