Radiotherapy for gastric mucosa-associated lymphoid tissue lymphoma  

作　　者：Laurent Quéro Mouna Labidi Marc Bollet Côme Bommier Sophie Guillerm Christophe Hennequin Catherine Thieblemont 

机构地区：[1]Department of Radiation Oncology,AP-HP,Saint Louis Hospital,Paris 75010,France [2]Faculty of Medicine,Universitéde Paris,Paris 75005,France [3]Department of Radiation Oncology,Hartmann Oncology Radiotherapy Group,Levallois-Perret 92044,France [4]Hemato-Oncology,DMU DHI,AP-HP,Saint Louis Hospital,Paris 75010,France

出　　处：《World Journal of Gastrointestinal Oncology》2021年第10期1453-1465,共13页世界胃肠肿瘤学杂志（英文版）（电子版）

摘　　要：Gastric mucosa-associated lymphoid tissue(MALT)lymphoma is a rare disease which is often associated with Helicobacter pylori(H.pylori)infection.First-line treatment of stage IE and IIE localized gastric MALT lymphoma is based on the eradication of H.pylori.The presence of H.pylori resistance factors such as translocation t(11;18),peri-gastric lymph node involvement and the degree of tumor infiltration of the gastric wall;or lack of response to antibiotic therapy are two main indications to treat with definitive radiotherapy(RT).RT is an effective treatment in localized gastric MALT lymphoma.A moderate dose of 30 Gy allows a high cure rate while being well tolerated.After treatment,regular gastric endoscopic follow-up is necessary to detect a potential occurrence of gastric adenocarcinoma.

关 键 词：RADIOTHERAPY Mucosa-associated lymphoid tissue MALT Helicobacter pylori LYMPHOMA REVIEW 

分 类 号：R735.2[医药卫生—肿瘤]