临床常见快速进展前列腺癌临床特点及研究进展  

Research progress and clinical characteristics of clinical rapidly progressing prostate cancer

作　　者：史本康[1] 陈守臻[1] 曲思凤[1] 王勇[1] 刘磊[1] SHI Benkang;CHEN Shouzhen;QU Sifeng;WANG Yong;LIU Lei(Department of Urology,Qilu Hospital of Shandong University,Jinan 250012,Shandong,China)

机构地区：[1]山东大学齐鲁医院泌尿外科,山东济南250012

出　　处：《山东大学学报（医学版）》2021年第9期110-116,共7页Journal of Shandong University:Health Sciences

基　　金：国家自然科学基金面上项目(81970661)。

摘　　要：前列腺癌是男性最常见恶性肿瘤之一。部分前列腺癌患者疾病进展迅速,短时间内出现复发、转移以及耐药,导致预后不良。准确识别快速进展前列腺癌,采取相应的针对性治疗可使患者生存获益。论文对常见的快速进展前列腺癌类型及其临床、病理和分子学特征进行总结。Prostate cancer is one of the most common malignant tumors in men. Some prostate cancer patients experience rapid disease progression, with recurrence, metastasis and drug resistance in a short period of time, leading to a poor prognosis. Accurately identifying rapidly progressing prostate cancer and taking corresponding treatments can provide survival benefits. This review summarizes the common types of rapidly progressing prostate cancer and their clinical, pathological and molecular characteristics.

关 键 词：快速进展前列腺癌 神经内分泌 前列腺导管内癌 基因突变 

分 类 号：R737.25[医药卫生—肿瘤]