不同年龄阶段健康成年人群的非线性脑电分析  

Non-linear electroencephalogram analysis of healthy adults in different ages

作　　者：柯莎[1] 廖波[2] 杨飞[1] 王寅旭[1] KE Sha;LIAO Bo;YANG Fei;WANG Yin-xu(Department of Neurology,Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,Sichuan,China;Department of Urology,Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,Sichuan,China)

机构地区：[1]川北医学院附属医院神经内科,四川南充637000 [2]川北医学院附属医院泌尿外科,四川南充637000

出　　处：《川北医学院学报》2021年第10期1294-1297,共4页Journal of North Sichuan Medical College

基　　金：四川省基层卫生事业发展研究中心课题(SWFZ21-C-113);四川省医学科研课题(S19029)。

摘　　要：目的:探讨不同年龄段健康成年人群的非线性脑电特征。方法:根据不同年龄段将158名健康成年人分为青年组(n=38)、中年组(n=41)、年轻老年组(n=39)和老年组(n=40),分析各组脑电非线性参数复杂度(complexity,Cx)和近似熵(approximate entropy,ApEn)值的特点,比较四组受试者全脑区以及不同脑区的Cx和ApEn的差异性。结果:老年组的Cx和ApEn值与其它三组两两比较,差异均有统计学意义(P<0.05),而其余三组两两相比则无统计学差异(P>0.05)。结论:非线性分析参数Cx和ApEn可定量、准确地反应皮层功能状态,可初步用于监测大脑皮层功能的变化。Objective:To explore the non-linear Electroencephalogram(EEG)characteristics of healthy adults in different ages.Methods:158 healthy adults were selected and divided into four groups:Young group(n=38),Middle-aged group(n=41),Young-old group(n=39),Old-old group(n=40),and analyzed the EEG nonlinearity in each group,contain the characteristics of parameter complexity(Cx)and approximate entropy(ApEn)values,then compared the Cx and ApEn mean values of the whole brain area of the four groups,and also compared the differences of Cx and ApEn values in different brain areas.Results:The Cx and ApEn values of the Old-old group were statistically different from the other three groups(P<0.05),while the other three groups were not statistically different(P>0.05).Conclusion:The non-linear analysis parameters Cx and ApEn can quantitatively and more accurately reflect the functional state of the cortex,and can be used to monitor changes in the cerebral cortex function.

关 键 词：脑电图 复杂度 近似熵 非线性分析 健康成年人群 

分 类 号：R741.044[医药卫生—神经病学与精神病学]