Cerebrospinal Fluids from Patients with Five Common Genetic Prion Diseases in China Display Distinct Reactivities in the RT-QuIC Assays  

作　　者：HU Chao CHEN Cao CHEN Jia XIAO Kang ZHOU Wei XIA Ying YANG Wei WANG Lin SHI Qi DONG Xiao Ping 

机构地区：[1]State Key Laboratory for Infectious Disease Prevention and Control,Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases(Zhejiang University),National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China [2]Center for Biosafety Mega-Science,Chinese Academy of Sciences,Wuhan 420115,Hubei,China [3]College of Life Science and Technology,Heilongjiang Bayi Agricultural University,Daqing 163711,Heilongjiang,China [4]China Academy of Chinese Medical Sciences,Beijing 100700,China [5]Center for Global Public Health,Chinese Center for Disease Control and Prevention,Beijing 102206,China

出　　处：《Biomedical and Environmental Sciences》2021年第10期830-833,共4页生物医学与环境科学（英文版）

基　　金：National Natural Science Foundation of China[81772197,81401670,81630062];National Key Research and Development Program of China[2018YFC1200305];National Science and Technology Major Project of China[2018ZX10102001];SKLID Development Grant[2019SKLID401,2019SKLID603,2016SKLID603];the Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences[2018RC330004]。

摘　　要：Prion diseases(PrDs)are fatal neurodegenerative conditions that affect humans and other mammals,which consist of sporadic,genetic,and acquired forms in human PrDs[1].The genetic form accounts for approximately 5%–15%of all human PrDs.

关 键 词：DISEASES PATIENTS ASSAY 

分 类 号：R373[医药卫生—病原生物学]