可溶性膳食纤维联合益生菌治疗老年便秘型肠易激综合征的临床疗效观察  

Clinical efficacy of soluble dietary fiber in treatment of irritable bowel syndrome with predominant constipation in the elderly

作　　者：张旭[1] 林晚 朱利涛 阮继刚[1] 张飞雄[1] ZHANG Xu;LIN Wan;ZHU Li-tao;RUAN Ji-gang;ZHANG Fei-xiong(Gastroenterology,General Hospital of Ningxia Medical University,Yinchuan,Ningxia 750004,China;不详)

机构地区：[1]宁夏医科大学总医院消化内科,宁夏银川750004 [2]银川监狱医院门诊部,宁夏银川750001

出　　处：《中国微生态学杂志》2021年第9期1082-1085,共4页Chinese Journal of Microecology

摘　　要：目的观察可溶性膳食纤维联合益生菌治疗老年便秘型肠易激综合征的临床疗效及安全性。方法将2017年1月至2019年1月本院就诊的130例老年便秘型肠易激综合征患者随机分为膳食纤维联合益生菌组、益生菌组和膳食纤维组。膳食纤维联合益生菌组患者服用可溶性膳食纤维联合双歧杆菌三联活菌片,益生菌组口服双歧杆菌三联活菌片,膳食纤维组使用可溶性膳食纤维,三组疗程均为30 d。比较三组患者症状改善情况、PAC-QOL评分、CSI评分。结果三组患者治疗后PAC-QOL评分、CSI评分较治疗前显著减低,且膳食纤维联合益生菌组治疗后PAC-QOL评分均低于益生菌组和膳食纤维组,差异有统计学意义(P<0.05)。膳食纤维联合益生菌组患者治疗后临床总有效率较益生菌组和膳食纤维组明显增高,差异有统计学意义(P<0.05)。结论可溶性膳食纤维联合益生菌治疗老年便秘型肠易激综合征患者效果显著,无明显不良反应。Objective To observe the clinical efficacy and safety of soluble dietary fiber combined with probiotics in the treatment of elderly constipation predominant irritable bowel syndrome(CP-IBS). Methods One hundred and thirty elderly patients with CP-IBS in our hospital from January 2017 to January 2019 were randomly divided into observation group, probiotics group or dietary fiber group. Patients in the observation group were treated with soluble dietary fiber combined with Bifidobacterium triple viable tablets for 30 days. Probiotics group took Bifidobacterium triple viable tablets for 30 days. Dietary fiber group was treated with soluble dietary fiber for 30 days. The improvement of symptoms, PAC-QOL score and CSI score were compared among the three groups. Results After 30 days, the PAC-QOL score and CSI score in the three groups were significantly lower than those before treatment, and the PAC-QOL score in the observation group after treatment was lower than that in the probiotics group and dietary fiber group respectively;the difference was statistically significant(P<0.05). After treatment, the total efficiency rate in observation group was significantly higher than in probiotics group and dietary fiber group respectively(P<0.05). Conclusion The effect of soluble dietary fiber combined with probiotics in the treatment of elderly patients with CP-IBS was significant, without obvious adverse reactions.

关 键 词：可溶性膳食纤维 益生菌 老年 便秘型肠易激综合征 

分 类 号：R574[医药卫生—消化系统]