γ-环糊精工业化生产的研究进展  

Research progress in industrial production ofγ-cyclodextrin

作　　者：柏玉香[1,2,3] 吴浩 BAI Yuxiang;WU Hao(State Key Laboratory of Food Science and Technology,Jiangnan University,Wuxi 214122,China;School of Food Science and Technology,Jiangnan University,Wuxi 214122,China;Synergetic Innovation Center of Food Safety and Nutrition,Jiangnan University,Wuxi 214122,China)

机构地区：[1]江南大学,食品科学与技术国家重点实验室,江苏无锡214122 [2]江南大学食品学院,江苏无锡214122 [3]江南大学,食品安全与营养协同创新中心,江苏无锡214122

出　　处：《食品与发酵工业》2021年第22期279-287,共9页Food and Fermentation Industries

基　　金：国家自然科学基金面上项目(32072268);食品科学与技术国家重点实验室自主研究课题(SKLF-ZZB-202007)。

摘　　要：γ-环糊精(γ-cyclodextrin,γ-CD)是淀粉底物经酶法转化获得的产品,在食品、药品和化妆品等领域展现了良好的功能特性和应用价值。目前,γ-CD的生产技术被欧美日等发达国家垄断,价格居高不下。为了突破瓶颈,探索γ-CD国产化道路,该文先从γ-CD的理化特性、应用原理、市场潜力和法律法规等方面概述了产品的核心要义,再从淀粉预处理、环糊精葡萄糖基转移酶(cyclodextrin glycosyltransferase,CGT酶)筛选、络合剂选择与去除以及产物鉴定等流程总结了生产工艺的流程关键点,最后就γ-CD工业化生产中的限制性因素展开系统性的分析与讨论。该文旨在梳理瓶颈问题,为γ-CD的国产化和规模化应用推广提供参考和支撑。γ-Cyclodextrin(γ-CD)is produced from starch by enzymatic transformation technology.It is of fantastic functional characteristics and application value in the fields of food,medicine and cosmetics.At present,the production technology ofγ-CD is monopolized by developed countries such as Europe,America and Japan,resulting in its high prices.To break through the bottleneck and to explore the domestic production way ofγ-CD,this review first summarized the core essence ofγ-CD from the aspects of physical and chemical properties,application principles,market potential,laws,and regulations.Then,the key points of the production process were summarized from the processes of starch pretreatment,selection of cyclodextrin glycosyltransferase(CGTase),selection and removal of complexing agent,and product identification.Finally,a systematic analysis and discussion on the restrictive factors in the industrial production ofγ-CD were carried out which aimed to sort out bottlenecks and provide reference and support for the domestic and large-scale production ofγ-CD.

关 键 词：γ-CD 淀粉 络合剂 生产工艺 

分 类 号：O636.12[理学—高分子化学]