Functional hemispherectomy for patients with adult-onset Rasmussen’s encephalitis  

作　　者：Hong Xue Cuiping Xu Xiaoxia Zhou Duanyu Ni Xueyuan Wang Tao Yu 

机构地区：[1]Beijing Institute of Functional Neurosurgery,Xuanwu Hospital,Capital Medical University,No.45 Changchun Street,Beijing 100053,China [2]Department of Neurology,The second Clinical Medical College of Guizhou University of traditional Chinese Medicine,Guiyang 550001,Guizhou,China

出　　处：《Acta Epileptologica》2021年第1期77-81,共5页癫痫学报（英文）

基　　金：supported by National Natural Science Foundation of China(Grant No.81771395).

摘　　要：Background:Surgical treatment for patients with adult-onset Rasmussen’s encephalitis(A-RE)is rarely reported.We investigated the clinical and surgical features of two patients with A-RE who underwent functional hemispherectomy.Case presentation:The data of clinical manifestations,neuroimaging,surgical treatment and surgical outcomes of two patients with A-RE was reviewed.The two patients initially presented with recurrent partial seizures or secondly generalized tonic clonic seizures.Gradually,the patients showed unilateral limb paralysis as well as chronic focal epileptic status.Both patients underwent functional hemispherectomy and achieved seizure freedom in the followup.The contralateral neurological deficits improved gradually after rehabilitation and were acceptable for the selfcare of daily living.The living quality improved prominently after surgery.Conclusions:Despite the risk of hemiplegia,functional hemispherectomy may be a choice for patients with A-RE for favorable seizure control and improved quality of life in selected patients.

关 键 词：Rasmussen encephalitis ADULT EPILEPSY HEMISPHERECTOMY 

分 类 号：R73[医药卫生—肿瘤]