分时段不同中药治疗缺血性心肌病气虚血瘀阻络型心衰的远期疗效观察  

Observation on Long-term Clinical Effects of Phased TCM Therapies in the Treatment of Qi Deficiency,Blood Stasis Obstructing Collaterals Pattern Heart Failure Caused by Ischemic Cardiomyopathy

作　　者：黄瑞霞[1] 王仁平[1] 王宁宁[1] 张敏[1] 赵洁 崔静 何美娟[1] HUANG Ruixia;WANG Renping;WANG Ningning;ZHANG Min;ZHAO Jie;CUI Jing;HE Meijuan(The First Cardiovascular Department,Shijiazhuang Changcheng Hospital of Integrative Medicine,Shijiazhuang 050035,China)

机构地区：[1]石家庄长城中西医结合医院心血管一科,河北石家庄050035

出　　处：《西部中医药》2022年第1期105-108,共4页Western Journal of Traditional Chinese Medicine

基　　金：河北省中医药管理局项目(2016113)。

摘　　要：目的:观察分时段采用不同中药方剂治疗缺血性心肌病气虚血瘀阻络型心衰的远期临床疗效。方法:将缺血性心肌病气虚血瘀阻络型心衰患者120例按照随机对照原则分为治疗组(心肌活力饮、冠脉疏通饮+西药治疗)和对照组(西药治疗)各60例,治疗4周后评估疗效,随访3个月比较两组患者心血管事件发生率及生活质量。结果:总有效率治疗组为90.00%,高于对照组的66.67%;治疗组心衰分级轻度占63.33%,高于对照组的33.33%;治疗组心血管事件总发生率为6.67%,低于对照组的20.00%(P<0.05)。治疗组躯体健康(physical component summary,PCS)总评分与心理健康(mental component summary,MCS)总评分均高于对照组(P<0.05)。结论:根据人体阴阳消长,早晨服用心肌活力饮益气解毒,晚上服用冠脉疏通饮活血通络能降低缺血性心肌病气虚血瘀阻络型心衰患者心血管事件发生率,帮助提高患者生活质量。Objective:To observe long-term clinical effects of phased TCM therapies in the treatment of Qi deficiency,blood stasis obstructing collaterals pattern heart failure caused by ischemic cardiomyopathy.Methods:All 120 patients were divided into the treatment group(Xinji Huoli drink,Guanmai Shutong drink+Western medicine therapy)and the control group(Western medicine therapy)according to randomized control principles,with 60 cases in each group,after four weeks of treatment,to assess clinical effects,to compare the incidence of cardiovascular events and quality of life when the patients were followed up for three months.Results:Total effective rate of the treatment group was 90.00%,higher than 66.67%of the control group;mild heart failure held 63.33%in the treatment group,higher than 33.33%of the control group;the total incidence of cardiovascular events of the treatment group was 6.67%in the follow-ups,lower than 20.00%of the control group(P<0.05).In the follow-ups,total scores of PCS and MCS of the treatment group were higher than these of the control group(P<0.05).Conclusion:Based on waxing and waning of Yin and Yang in human body,the administration of Xinji Huoli drink in the morning could benefit Qi and remove toxin,taking Guanmai Shutong drink in the evening could activate blood and dredge the collaterals,which could lower the incidences of cardiovascular events of the patients and help improve quality of life in patients.

关 键 词：缺血性心肌病 气虚血瘀阻络 心衰 心血管事件 生活质量 分时段 

分 类 号：R223[医药卫生—中医基础理论]