Advances on Current Techniques and Methodologies in Milk Lipidomics  

作　　者：Li Mo-han Rayhnigul Abdlla Chen Jia-li Liu Yi-ming Zhang Xiu-min Cao Xue-yan Yang Mei Zheng Yan Yue Xi-qing 

机构地区：[1]College of Food Science,Shenyang Agricultural University,Shenyang 110866,China [2]Department of Foreign Languages,Shenyang Agricultural University,Shenyang 110866,China [3]Beijing Academy of Food Sciences,Beijing 100068,China

出　　处：《Journal of Northeast Agricultural University(English Edition)》2021年第4期25-37,共13页东北农业大学学报（英文版）

基　　金：Supported by"the 13th Five-Year"National Science and Technology Plan Project of China(2018YFC1603703,2018YFC1604302);the National Natural Science Foundation of China(2013BAD18B03);China Scholarship Council(202008210391);Shenyang Technological Innovation Project(Y17-0-028);Liaoning Revitalization Talents Project(XLYC1902083);Postgraduate Innovation and Cultivation Project of Shenyang Agricultural University(2021YCXB04)。

摘　　要：Milk is a complex biological fluid containing lipids,proteins,carbohydrates and minerals,which are essential for infant growth.While the lipid portion constitutes only 3%-5%of the total milk composition,it accounts for over 50%of the infant’s daily energy intake.The dominant portion(approximately 98%)is in the form of triacylglycerols and polar lipids,such as glycerophospholipids and sphingolipids,forming minor components.Recently,with the development of lipidomics,important progresses have been made in milk lipidomics,and the identification and quantification of several milk lipids at the group and molecular species level has become a reality,thereby providing useful information for the infant formula industry.In this review,an overview of the separation of the main components of milk lipids was presented,including glycerolipids,phospholipids and sphingolipids.The analytical methods and strategies for milk lipidomics,including gas chromatography-mass spectrometry(MS),capillary electrophoresis MS,nuclear magnetic resonance,matrix-assisted laser desorption ionization-MS,electrospray ionization-MS,shotgun lipidomics and liquid chromatography-MS,were reviewed.Additionally,the bioinformatics of lipidomics for milk lipid determination,including lipid classification,lipid databases and lipid analysis software,were investigated.This review would aid future investigations of the nutrition of milk lipids and refined researches on formula milk powder.

关 键 词：MILK LIPIDOMICS triacylglycerols GLYCEROPHOSPHOLIPIDS SPHINGOLIPIDS 

分 类 号：TS252.1[轻工技术与工程—农产品加工及贮藏工程]