朊蛋白病所致精神障碍误诊为抑郁发作1例  

Mental disorder caused by prion disease misdiagnosed as depressive episode:a case report

作　　者：肖心怡 张新 苏中华 Xiao Xinyi;Zhang Xin;Su Zhonghua(School of Mental Health,Jining Medical University,Jining 272067,China;Daizhuang Hospital of Shandong Province,Jining 272051,China)

机构地区：[1]济宁医学院精神卫生学院,山东济宁272067 [2]山东省戴庄医院,山东济宁272051

出　　处：《四川精神卫生》2022年第1期77-79,共3页Sichuan Mental Health

摘　　要：本文报告一例29岁的朊蛋白所致精神障碍被误诊为伴躯体症状的抑郁发作的男性患者,患者首发症状主要为精神症状,后出现进行性加重的躯体症状,距首次发病一年余死亡。朊蛋白病引起的精神症状表现多样,易导致漏诊和误诊。本文通过对该案例进行讨论,以期为临床医生对诊断朊蛋白病所致精神障碍提供参考。This paper reported a case of a 29-year-old male patient with mental disorder caused by prion disease was misdiagnosed as depressive episode with somatic symptoms.The patient's symptoms were initially predominantly psychiatric,with progressive worsening of somatic symptoms,and he died more than 1 year after his first onset.Prion disease caused various manifestations of mental symptoms,which can easily lead to missed diagnosis and misdiagnosis.This paper discussed the case,in order to provide references for the clinical diagnosis of mental disorder caused by prion disease.

关 键 词：朊蛋白病 伴躯体症状的抑郁发作 精神症状 

分 类 号：R749[医药卫生—神经病学与精神病学]